Design Of Neonatal Dynamic Percutaneous Jaundice Based On Dual-wavelength Method

Nowadays,the general procedure for the monitoring of neonatal jaundice is micro blood measurement,taking into account the damage on neonatal exsanguinating,percutaneous jaundice meter can be used as an important indicator of clinical measurement reference,but there is a lack of a dynamic way to measure percutaneous jaundice,can not obtain information on neonatal bilirubin concentration changes immediately.To meet the requirements of being noninvasive,portable and dynamic monitoring,the principle and characteristics of optical detection of chaotic medium with dual-wavelength method were studied.The Lamber-Beer law and the optical properties of human skin tissue were then discussed.Based on dual-wavelength method optical detection principle,select biosensor AFE4403 analog front-end to design photoelectric detection probe,combined with MCU,Bluetooth,power supply module to build the whole system,complete the software and hardware design,and then perform the simulated experiments and clinical calibration experiments,studies the theory of human signal processing,such as Wavelet de-noising,data fitting,The experimental calibration results show that there is a significant linear relationship between the measured signal value and the standard value,preliminary verification of the measurement results could reflect the trend of neonatal bilirubin.In addition,the jaundice design noninvasive detection module with low power consumption,small size,continuous measurement and other characteristics,and also add Bluetooth functionality,the data can be uploaded to the host computer or phone in real time,enabling real-time monitoring and early warning,facilitating clinical or household monitoring,this project has great significance for neonatal health.