Changes Of Serum Sugar And Fat In Sows Without Special Blight During Perinatal Period

Objective:To explore the dynamic changes of serum energy metabolism related indicators in perinatal sows,and then to provide the reference for understanding the biology of perinatal sows and improving the breeding management of sows.Methods: Firstly,six common infectious diseases,namely,pseudorabies,swine fever,foot-and-mouth disease,Porcine reproductive and respiratory syndrome,Porcine circovirus disease and porcine epidemic diarrhea,were screened before the trial.Only pigs with negative results were recruited in the present study.Blood samples were collected at 6 time points from 3 weeks before delivery to 3 weeks after delivery.In total,180 blood samples were collected.Commercially available kits were used to determine serum carbohydrate and lipid metabolism indices,including glucose(GLU),lactic acid(LD),lactate dehydrogenase(LDH),hexokinase(HK),pyruvate kinase(PK),pyruvate(PA),beta-hydroxybutyric acid(BHBA),triglycerides(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL),low density lipoprotein cholesterol(LDL)and very low density lipoprotein(VLDL),free fatty acid(NEFA),lipase(LPS),etc.Results:Serum NEFA,BHBA and GLU levels at 1 week before delivery were significantly higher than those postpartum(p<0.05);Serum levels of TG,VLDL and LDL at3 weeks and 2 weeks before delivery were significantly higher than those postpartum(p<0.05);while HDL levels at 2 weeks before delivery were significantly lower than those postpartum(p<0.05);Serum TC levels at 2 and 3 weeks postpartum were significantly higher than those at other stages(p<0.05);Serum LDH at 1 week before delivery was significantly higher than that at 2 weeks before delivery(p<0.05),and the ratio of LD to PA was the highest at this time point;levels of serum PK at 3 weeks before delivery were significantly higher than that at 3 weeks after delivery(p<0.05);serum HK level at 3 weeks before delivery and 3 weeks after delivery was significantly higher than that at 1 week before delivery(p<0.05);serum LPS level at 1 week before delivery was significantly higher than that at other stages(p<0.05).Conclusion:Perinatal sows display disorders of glucose and lipid metabolism and attentions should be paid to during the management of perinatal sows.