Clinical Observation On The Therapeutic Effects Of Jiawei Xiaqi Tang Treating FD Due To Spleen Deficiency And Qi Stagnation

Background:Functional dyspepsia(FD)is a common and frequently-occurring disease in department of Gastroenterology.Its symptoms often persist or occur repeatedly,which seriously affects the quality of life of patients and causes a very heavy burden on the family and the world.Although FD is a common disease,its etiology and pathogenesis is still unclear.And its treatment also lack of a drug that can make the symptoms of FD completely relief and no longer appear.Besides,long term to take the medicine may cause lots of adverse reactions.Traditional Chinese Medicine(TCM)is base on the integrated view,values on the unity of portion and the whole body,combines with the disease and syndrome,so it has a rich experience on treating FD.By catching the macro level,varying treatment to different syndrome,regulating the patient's physique and individualizing for each patient,TCM can lessen FD recur,improve the quality of patient's life and adjust their mentality,so it deserve to further research,promote and apply.Objective:Observing the therapeutic effects of Jiawei Xiaqi Tang treating FD due to Spleen Deficiency and Qi Stagnation,and making a preliminary discussion of the mechanism of Jiawei Xiaqi Tang in terms of theoretical and clinical research,to provide new ideas for FD treatment.Methods:According to the principle of stochastic and antithesis,randomly divided 60 patients with FD due to Spleen Deficiency and Qi Stagnation who conforms the diagnosis standards into experiment group and control group,each group 30 cases.The experiment group was given Jiawei Xiaqi Tang,twice a day,separately before breakfast and dinner.The control group was given Mosapride Citrate,5mg,3 times a day,30 minutes before meals.Two groups were treated 4 week for one course of treatment.Observe the efficacy indicators of the two groups before and after treatment and the incidence of adverse reactions,record and analyze the data of the two groups.Results:After the course of treatment,the total efficiency of the experimental group was 93.33%and the control group was 76.67%.By statistical analyzing the data,it means it has a significant difference between the two groups(P<0.05).Both the two groups can relief the patient's symptoms and have no significant different on epigastric or abdominal distention,epigastric pain,eat less,nausea and vomiting,fatigue,bowel movement(P>0.05).Compare to the control group,the bowel movement of the experimental group has improved by statistical analysis(P<0.05).And there is significant different that the experimental group can relief the symptom of belching reflux comparing to the control group(P<0.01).Conclusion:Jiawei Xiaqi Tang has a better clinical efficacy in treating FD due to Spleen Deficiency and Qi Stagnation compared with the control group.