Clinical Study Of Yu Yin Li Shui Gao In The Treatment Of Refractory Ascites Electrolyte Disorder And Acid-base Imbalance In Liver And Kidney Yin Deficiency Type Cirrhosis

Objective:To observe the effect of YuYin LiShuiGao on the imbalance of electrolyte and acid-base imbalance in patients with liver and kidney Yin deficiency cirrhosis,and its clinical curative effect.Objective to evaluate the safety and efficacy of yuyin rehydration cream,To further reduce the complications of cirrhosis patients with refractory ascites,improved prognosis and prolonged survival,it provides a useful reference for clinical treatment of refractory ascites of cirrhotic cirrhosis.Methods:The 60 patients with inclusion criteria were randomly divided into two groups,the treatment group and control group received 30 cases.The two groups were treated with 1 week and 2 courses.Control group:To correct electrolyte disordered,acid,diuretic,discontinuous infusion albumin and other symptomatic treatment.Treatment group:On the basis of the control group,YuyinLiShuiGao was added,with 30ml each time,three times a day,and warm water after the meal.In the first and second weeks before and after treatment,the differences in weight,abdominal circumference,color doppler flow,electrolyte,blood gas,liver and kidney function,and TCM syndrome score were observed,after the observation,the data were statistically analyzed to compare the difference of efficacy between the two groups.Results:Comparison between groups:（1）At the end of the seventh day,the treatment group was lower than the control group in abdominal circumference,body weight,color doppler flow,PH and TCM syndrome;The24-hour urine volume,K⁺,Na⁺,Cl^-and PaCO₂ were all higher than the control group,the difference was statistically significant;There was no statistically significant difference between Ca²⁺,HCO₃^-,BE,ALT,AST,TBIL and ALB.（2）At the end of the 14th day,the treatment group was lower than the control group,including abdominal circumference,body weight,color doppler flow,PH,TCM syndromes,ALT,AST and TBIL,the 24-hour urine volume,PaCO₂,K⁺,Na⁺,Cl^-and ALB were all higher than the control group.the difference was statistically significant;There was no statistically significant difference between Ca²⁺,HCO₃^-and BE.（3）After the 14th day of treatment,the two groups showed significant difference in efficiency and total efficiency,and the difference was statistically significant,and the treatment group was superior to the control group.Comparison within the group:（1）At the end of the seventh day,two groups of abdominal circumference,weight,and color ultrasound were lower than before treatment,the urine volume was higher in 24 hours than before treatment,the differences were statistically significant,The PH and TCM syndromes of the treatment group were lower than before treatment,K⁺,Na⁺,Cl^-and PaCO2 were all higher than before treatment,and the differences were statistically significant,there was no statistically significant difference between the control group and the control group.There was no statistically significant difference between the two groups of HCO3-,BE,ALT,AST,TBIL and ALB before treatment.（2）At the end of the 14th day,Two groups of abdominal circumference,body weight,color doppler flow and TBIL were lower after the 7th day of treatment,the 24-hour urine volume was higher after the end of the 7th day of treatment,the differences were statistically significant.Treatment group K⁺,Na⁺,Cl^-,PH,PaCO₂,TCM syndrome differentiation,ALT,AST,ALB and treatment were different after the 7th day of treatment,and the difference was statistically significant,there was no statistically significant difference between the control group and the treatment group at the end of the 7th day.There was no statistically significant difference between the two groups of Ca²⁺,HCO3^-and BE.（3）At the end of the 14th day,two groups of abdominal circumference,body weight,color doppler flow,TCM syndrome,AST and TBIL were all lower than before treatment,and the24-hour urine volume,K⁺and Na⁺were higher than before treatment,and the differences were statistically significant.In the treatment group,PH and ALT were lower than before treatment,and Cl^-,PaCO₂ and ALB were increased before treatment,and the differences were statistically significant,and the control group was not statistically significant.There was no statistically significant difference between the two groups of Ca²⁺,HCO₃^-and BE.Conclusion:YuYinLiShuiGao has the clinical symptoms of patients with refractory ascites in cirrhosis,it has good nourishing effect of nourishing the liver and invigorating spleen and water.YuYin LiShuiGao can improve the electrolyte disturbance and acid and alkali imbalance of refractory ascites patients in cirrhosis.There was no adverse reaction to the whole experiment,YuYinLiShuiGao is a safe and reliable method.