The Language Lateralization Among The Chinese Native Adult Speakers With Right-handed By Functional Transcranial Doppler

Object:To assess the language lateralization in Chinese native adult speakers using functional transcranial doppler(f TCD),and explore whether gender or age has an influence on language lateralization in Chinese native adult speakers.Patients and methods:A total of 98 healthy volunteers,who were admitted to No.1Hospital of Jilin University from June 2016 to August 2016,3 of them were not involved in the statistical evaluation because of the unilateral or bilateral temporal window penetration in one women and the head movement during the task in one man and one women.Participants were evaluated by the Hamilton Anxiety scale(HAMA),the Hamilton Depression scale(HAMD)and the language items in the Wechsler Adult Intelligence Scale(WAIS)before the task.The functional transcranial doppler and the transcranial doppler examination of the above subjects were examined by the experienced doctor Han,department of Neurological Head and neck vascular ultrasound Center.The chinese semantic fluency task was according to English language lateralizationtest-semantic fluency task.Participants were also monitored for the flow velocity of the middle cerebral arteries while performing the semantic fluency task in Chinese.The examiner was unaware of the clinical condition of the subjects.The demographic data,including the gender,age,fours evaluation scales and whether there is a history of hypertension,stroke,diabetes or hyperlipidemia.The LI describing both hemispheric dominance and degree of lateralization.The positive value represents the left domination,the negative value represents the right domination,the greater of the absolute value means the greater of the lateralization,zero means no lateralization.Results:1.The language lateralization,among the Chinese native adult speakers with right-handed mainly showed left,and its percentage was 67.4%.The average LI of the left domination was 5.85±2.31,while the average LI in the right domination was 5.32 ± 1.63,and there was no difference between the two kinds of dominations(P>0.05);2.Age and sex did not affect language lateralization in the direction or the degree.There was no correlation between age and the degree of the language lateralization of the Chinese native adult speakers.Conclusions:1.The language lateralization among the Chinese native adult speakers with right-handed mainly showed left,which is consistent with previousf MRI studies.f TCD can be used as one of the methods to study Chinese language lateralization.2.Age and gender had no influence on the direction and the degree of language dominance,and age was not correlated with language dominance.