| Objective:1.To observe the clinical efficacy and safety of gout in the treatment of acute rheumatoid arthritis..Methods:the method used in this study was random and controlled,and 60 cases of patients with acute rheumatoid arthritis of the acute phase of arthritis were treated with 30 cases and 30 patients in the control group.The control group was given to etoxix tablets(Merck)60 mg,1 day,orally;Colchicine tablets(xishuangbanna pharmaceutical)0.5 mg,3 times on 1 day,orally;The treatment group was given etoxix tablets(Merck)60 mg,1 day,orally;Colchicine tablets(xishuangbanna pharmaceutical)0.5 mg,1,3,oral,gout,in addition to the certification of soup decoction(fifth affiliated hospital,xinjiang medical university yinpian fry),200 ml,1,2,oral;The observation period was 2 weeks,and the dosage of colchicine was reduced to 0.5mg daily after treatment.To record the improvement of TCM syndromes and pain VAS scores on 1,3 and 7 days after treatment.The indexes of blood sedimentation,c-reactive protein and serum uric acid were recorded to evaluate the therapeutic effect after 2 weeks.The blood routine and renal function indexes were observed before and after treatment,and adverse reactions were recorded at any time to observe its safety..Results: 1,observe two groups of patients with 0,3,7,pain VAS score changes,statistical processing,3 days after treatment,with statistical significance(P < 0.05),7 after treatment compared,the results no statistical significance(P > 0.05).The treatment group was better than the control group.2,observe two groups of patients with 0,3,7,TCM syndrome integral,after statistics processing,compared two groups after treatment 3,the result was statistically significant(P < 0.05),the treatment group in improving the TCM syndrome in patients with early is better than that in control group.3.The changes of ESR and CRP after treatment were statistically treated,and the P value in the treatment group was < 0.05,which was statistically significant.The results of the two groups were not statistically significant,P BBB 0.0.05.4.Observe the occurrence of adverse reactions.Adversereactions in the control group showed 2 cases of stomach discomfort,diarrhea,1 case of vomiting,and no adverse reactions occurred in the treatment group.Conclusion: gout in the treatment of gout is better than those in the control group,and can improve the quality of life of patients.good security. |