Comparison Of Two Methods Of Bladder Reservation For Myometrial Invasive Bladder Cancer

Objective:To investigate the curative effect of T2N0M0 bladder cancer treated by two methods of transurethral resection of bladder tumor(TURBT)combined with intravenous chemotherapy and postoperative internal iliac arterial infusion chemotherapy.Methods: 54 patients with T2N0M0 bladder cancer were studied retrospectively,including 28 cases with TURBT combined with intravenous chemotherapy(control group),and 26 cases were treated with TURBT combined with internal iliac artery infusion chemotherapy(observation group).The general situation of the two groups,the perioperative situation and the incidence of postoperative adverse reactions were compared,and the 1 year survival rate,2 year survival rate,1 year recurrence rate and 2 year recurrence rate were statistically analyzed.Results: there was no significant difference in the general data between the 2 groups;the operation time of the observation group was(46.19 + 11.66)min,the amount of bleeding in the operation was(78.81 + 17.67)ml,the time of hospitalization was(5.96 + 1.37)d,the operation time of the control group was(46.79 + 11.90)min,the amount of bleeding in the operation was(80.36 + 15.09)ml,and the time of postoperative hospitalization was(6.61 + 1.50)d,there was no significant difference in the peri operative period of the two groups.There were 2 cases of nausea and vomiting,5 cases of routine urine abnormalities,3 cases of abnormal blood routine,2 cases of abnormal liver and kidney function,6 cases of nausea and vomiting,7 cases of abnormal urine,10 cases of abnormal blood routine,8 cases of abnormal liver and kidney function in the control group,and the blood constant in the observation group.The abnormalities of the regulation and the impairment of liver and kidney function were significantly lower than those of the control group.The difference between the 2 groups was statistically significant(P<0.05),but there was no significant difference between the 2 groups in the nausea and vomiting response and the urine routine abnormality.The 1 year,2 year survival rate and the 2 year recurrence rate of the 2 groups were not significant,and the 1 year recurrence rate of the observation group was significantly lower.In the control group(P<0.05).patients with bladder cancer at T2N0M0 stage were retrospectively studied,including 28 patients with TURBT combined with intravenous chemotherapy(control group)and TURBT combined with internal iliac arterial infusion chemotherapy(observation group)in 26 patients.The general conditions,perioperative conditions,occurrence of adverse reactions,etc.were compared between the two groups.The overall survival rate,1-year survival rate without relapse and 2-year survival rate without recurrence,were statistically calculated.Conclusion: For patients with T2N0M0 stage musculocutaneous invasive bladder cancer,TURBT combined with internal iliac artery infusion chemotherapy compared with postoperative combined intravenous chemotherapy,the recurrence rate of 1 years decreased significantly,and the abnormal blood routine and liver and renal function impairment were significantly decreased,which is worthy of clinical promotion.