Retrospective Analysis Of Efficacy And Restenosis Rate Of Domestic Biodegradable And Non-biodegradable Polymer Drug-eluting Stents In The Treatment Of Coronary Artery Disease

Objective :To determine whether the efficacy and restenosis rate of domestic biodegradable polymer drug-eluting stents(EXCEL)is superior to that of domestic non-biodegradable polymer drug-eluting stents(PARTNER)in the treatment of coronary artery disease(CAD).Methods:111 cases with CAD underwent percutaneous coronary intervention(PCI).Of them,54 patients were implanted with EXCEL stents and 57 patients with PARTNER stents.Main adverse cardiac events(MACE),recurrent angina,late stent thrombosis,restenosis rate,in-stent lumen loss and heart failurewere observed during follow-up.Results: There was no significant difference of the incidence of MACE,recurrent angina,late stent thrombosis,restenosis rate and heart failure between the two groups during follow-up of 6 to 30(13.6±6.8)months(all P>0.05).The percent of instent lumen loss≥30% was significant lower in EXCEL group(1.9%)than in PARTNER group(14.0%)(P=0.019).Conclusion :The efficacy and safety of EXCEL stent in the treatment of CAD are similar to that of PARTNER stent,while the percent in-stent lumen loss is lower.