Autogenous Morselized Bone Garft Versus Autogenous Iliac Bone Graft In The Treatment Of Single Segment Thoracic And Lumbar Spinal Tuberculosis

OBJECTIVE Retrospectively evaluate the clinical outcomes of autogenous morselized bone graft and autogenous iliac bone graft for single-segment thoracic and lumbar spinal tuberculosis.METHODS Between August 2012 to June 2016,58 cases of thoracic or lumbar spinal tuberculosis were treated by the surgery of interbody bone graft after debridment and fusion combined with posterior instrumentation.31 patients in group A using autogenous morselized bone graft and 27 cases in Group B using autogenous iliac bone graft.The operation time,blood loss,visual analog scale(VAS),Oswestry Disability Index(ODI),erythrocyte sedimentation rate(ESR),C-Reactive protein(CRP),The intervertebral height,segment-kyphotic angle were recorded and compared.The loss of segment kyphotic angle and intervertebral space height,and the bone fusion time on X-ray or CT scanning at the time point of post-operation and follow ups were recorded and compared.RESULTS Final follow-up time was an average of 26 months ranging from 15 to 38 months.The operation time was 194.2±34.9 minutes in group A and 240.0±61.5 minutes in group B(P<0.05).The blood loss was 282.2±130.0mL in group A and 540.7±276.6 mL in group B(P<0.05).The bone fusion time was 5.8±1.0 months in group A and 8.3±3.6 months in group B(P<0.05).Both group got good kyphosis correction and intervertebral height restoration.The loss of kyphosis correction and intervertebral height in group A were found to be more than those in group B,but with no significant difference between group A and group B(P>0.05).CONCLUSIONS Based on this retrospective study,autogenous morselized bone garft has a shorter operation time,lower blood loss and shorter bone fusion time compared with autogenous iliac bone graft.Autogenous morselized bone garft is a safe and effective way of bone graft in treating single-segment thoracic and lumbar tuberculosis.