Study On The Relation Between Rice Intake And Type 2 Diabetes Of Residents In Qingdao

Objective:To understand the rice consumption and type 2 diabetes(T2DM)in resident in Licang District of Qingdao city and explore the relationship between rice consumption and the risk of T2 DM.Methods: 35,509 subjects aged 30-79 years who had participated in Qingdao,Shandong province,China Kadoorie Biobank(CKB)study were chosen as our subjects in this study.Information about basic characteristics of subjects,physical examination,lifestyle habits,physical activities,personal and family illness and so on was obtained from the Qingdao,CKB study.In our study,basic characteristics of subjects,prevalence of type 2 diabetes and rice intake of residents were described.Related factors influencing the type 2 diabetes were analyzed by single factor Logistic regression model.The relation between rice intake and type 2 diabetes was analyzed again in multivariable Logistic regression model after controlling confounding factors.Interaction effects between rice consumption and T2 DM,diabetes family history,smoking alcohol consumption,physical activity,high blood pressure and BMI were also analyzed by Logistic regression model.Results: Among the 35509 subjects,men and women accounted for 44.0% and 56.0%,respectively.Average age of men and women was(49.4±10.0)and(51.0±10.3)years,respectively.Men's education and family income level were both higher than women(P<0.001),but women's hypertension prevalence was higher than male(P< 0.001).In this study,there were 3409 type 2 diabetes patients,among these patients,2059 were female and 1350 were male,the prevalence is 5.8%,3.8% respectively.Subjects eating rice for 0,1-3 times/month,1-3 times/week,4-6 times/week and at least 1time/day accounted for 4.0%,13.4%,4.0%,9.8% and 17.5%,respectively.With the increase of rice intake frequency,the average random blood glucose of groups values in different rice intake frequency groups were statistically significant(F=12.126,P<0.001).By gender stratification,the difference was also statistically significant in females(F=17.329,P<0.001),no statistically significant difference was found in males(F=0.921,P=0.921).Single factor Logistic regression analysis showed that high frequency of rice intake,high level of education,high income,lots of physical activity,siesta habit,high frequency of eating poultry,seafood products,aquatic products,fresh fruits were negatively related with type 2 diabetes disease(P<0.001),However,aging,female crowd,divorced,widowed,separation of marital status,sales,service and private owners and housework,retired,unemployed,laid-off and other occupations,smoking,drinking,family history of diabetes,hypertension,obesity,fasting for a long time,high frequency of pasta,meat in the diet and products,eggs and products,milk and products were positively related to type 2 diabetes disease(P<0.001).Multiple factor logistic regression analysis showed that rice consumption was negatively correlated with T2DM(OR=0.61,95%CI=0.50~0.74,P<0.05),after the adjustment for relevant confounding factors after controlling confounding factors.When stratified by gender,the association between rice consumption and the prevalence of T2 DM was only found in females(OR=0.46,95%CI=0.33~0.60,P<0.05).No statistical association was found in males(OR=0.80,95%CI=0.59~1.08,P=0.125).After controlling confounding factors,rice intake and family history of diabetes,alcohol consumption and BMI had negative multiplication interaction effects to T2 DM,and the values of interaction effects were 1.03(1.01~1.06),1.19(1.02~1.34)and 0.97(0.96~0.99).Conclusion: The risk of T2 DM may be reduced with the rice consumption,but further large cohort research is needed to confirm this.Rice consumption and family history of diabetes,alcohol consumption and BMI had negative interaction effects by multiplication model on the prevalence of T2 DM.