Base On Professor Liang Chao Heritage Experience And Ideas For Functional Gastrointestinal Disorders (FGID) Treatment With The Data Mining Techniques Research

Objective:Present in consideration of Professor Liang Chao heritage experience to use characteristics of TCM theory for Functional Gastrointestinal Disorders(FGID)treatment.The Treatment and drug discipline will research by the data mining techniques,in order to improve the clinical of TCM for treatment FGID ideas.Methods:Record all the Functional Gastrointestinal Disorders patients who treatment by Professor Liang Chao and also accord to Chinese and Western Medicine diagnostic criteria of the Functional Gastrointestinal Disorders total 205 cases,309 prescriptions.According to standardized information,including symptoms,tongue,pulse,medicine,prescription name,and then all the data records using Microsoft Office Excel 2010 software to establish a database.Using SPSS Statistics 23.0 software package for frequency analysis of Functional Gastrointestinal Disorders patients with TCM syndrome,syndrome type,commonly used herbs and also statistical analysis in different symptom.The measure of data association rules select SPSS Clementine12.0 software,using Apriori algorithm analysis for symptoms-symptoms,symptoms-Chinese medicine,Chinese medicine-Chinese medicine.Setting minimum support with 10%,minimum confidence with 60%.At last though the statistics will Summary Professor Liang Chao use TCM theory and clinical experience for FGID treatment.Results: The results of the data mining research on the analysis of Functional gastrointestinal disorders are shown as follows(1)Patient material:The number of female patients accounted for 60%,male 40%.The highest age group was 51-60 years old(81.5%).Diagnostic classification of FGID were Functional bowel disorders(38.5%),Functional gastroduodenal disorder(31.2%),Functional Esophageal disorders(15.1%),Functional abdominal pain(7.30%),Functional anorectal disorders(4.90%),Functional biliary disorders(3.00%).(2)Patient symptom:The highest tongue color was pale white(55.3%).The highest tongue coat was thin white coat(46.3%),Thick white coat(35.9%).The pulse more than 30% was deep & thready pulse(32.4%),weak & thready pulse(31.1%).A symptoms and signs of digestive system that above 30%(28 symptoms)were abdominal distension(63.1%),abdominal pain(53.7%),dry mouth(48.5%),belching(41.1%),bitter taste(39.5%),loose stools(31.1%).A symptoms of non-digestive system that above 30%(38 symptoms)were fatigued(58.9%),fear of cold(48.2%),irritability(46.3%),insomnia(44.0%),easy sweating(36.6%),fear cold food(32.4%).Correlation analysis of two symptoms about 11 lists,the highest confidence that more than 70% was abdominal distension with belching(72.44%),dizzy with fatigued(71.87%),acid regurgitation with belching(71.60%).Correlation analysis of three symptoms about 9 lists,,the highest confidence that more than 80% was dental ulcer with bitter taste and dry mouth(85.29%),difficult defecation with abdominal pain and fatigued(81.81%).(3)Diagnostic pathogenesis:Professor Liang Chao using diagnostic pathogenesis frequency more than 30% was Spleen yang qi deficiency(63.4%),Qi stagnation(61.8%),Yangming Heat accumulation(34.6%),Diet stagnation(32.7%).Correlation analysis of two diagnostic pathogenesis about 6 lists,the highest confidence that more than 80% was Taiyin deficient cold with Yangming Heat accumulation(91.83%),Qi stagnation with Spleen yang qi deficiency(84.81%).Correlation analysis of three diagnostic pathogenesis about 5 lists,the highest confidence that more than 80% was Liver hyperactivity with Spleen yang qi deficiency and Qi stagnation(85.45%),Diet stagnation with Spleen yang qi deficiency and Qi stagnation(85.33%),Diet stagnation with Qi stagnation and Spleen yang qi deficiency(85.33%),Liver hyperactivity with Qi stagnation and Spleen yang qi deficiency(83.92%).(4)Prescription and chinese herb :In number of 15 prescription,using more than 10% was Huangqijianzhong decoction(69.6%),Zhizhu pills(35.9%),Guifulizhong decoction(20.1%),Sijunzi decoction(15.5%),Banxiahoupu decoction(14.2%),Zhishixiaopi pills(13.6%).In number of 69 chinese herb,total frequency usage 5,466 time,using more than 80% was dried ginger(99.4%),fructus jujubae(98.7%),Radix Astragali seu Hedysari(97.7%),liquorice root(97.4%),Fructus Aurantii(95.8%),Massa Medicata Fermentata(95.8%),Cortex Cinnamomi(95.1%),Radix Aconiti Lateralis Preparata(92.9%),Radix Codonopsis(83.2%),Fructus Hordei Germinatus(81.9%).In number of 18 class of Chinese herb are using more than 7% was Qi-supplementing(27.53%),Warming interior(16.79%),Digestive(10.13%),Desiccating(7.92%),Activating Qi flowing(7.72%).Correlation analysis of two chinese herb are about 24 lists,correlation analysis of two chinese herb with symptom are about 16 lists.Conclusion: Present in consideration of Professor Liang Chao heritage experience to use chinese herbal for Functional Gastrointestinal Disorders(FGID)treatment in total 205 cases,309 prescriptions.Find out Professor Liang Chao using characteristics of TCM theory and chinese herbal experience.The core of Diagnostic pathogenesis were Spleen yang qi deficiency、Qi stagnation、Yangming Heat accumulation、Diet stagnation and Taiyin deficient cold.The therapy were add supplement of warming to spleen and stomach、Regulating activities internal organs of qi.The common using prescription were Huangqijianzhong decoction 、 Guifulizhong decoction、 Sijunzi decoction、Banxiahoupu decoction、Zhishixiaopi pills.As well as the main diseased region of FGID were Gastrointestinal dysfunction that similar with disbalance activities of spleen and stomach qi.