Study On The Differences Of Metabolic Diseases In Different Subtypes Of Obesity And Inflammatory State

Chapter 1 Prevalence of different obesity subtypes inpatients with abnormal diseaseObjective: To study the differences in the prevalence of dysplastic subtypes of different obese subtypes.Methods: Collected in April 2008 in Hunan Provincial People's Hospital physical examination center of the physical examination population,exclusion of incomplete data,a total of 3542 physical examination population into the study.Until December 2015,exclusion of incomplete data,374 cases of physical examination were followed up for 8 years into the study.Record the general situation,the relevant clinical and biochemical indicators.We used the criteria of American Cholesterol Education program(the National Cholesterol Education Programe,NCEP)in the third report(Adult Treatment Panel III,ATP-III)to define MS,MHO and other different metabolic status.MHO was defined as obesity without MS.Obesity abnormal metabolism was defined as obesity with MS.We used metabolically healthy normal weight group as normal control and investigate the differences in the prevalence of dysplastic subtypes of different obese subtypes.Results:1.The prevalence of hyperglycemia in obese abnormal metabolic group was significantly higher than normal metabolic group(P <0.05).The prevalence of hyperglycemia in MHOwas not increased(P> 0.05).2.The prevalence of NAFLD in MHO and obese abnormal metabolic group was significantly higher than normal metabolic group(P <0.05).The prevalence of NAFLD in metabolically unhealthy normal weight was not increased(P> 0.05).3.Hypertension and hyperlipidemia did not increase between different obese subtypes(P> 0.05).Conclusions:MHO does not increase the prevalence of hyperglycemia,obese abnormal metabolic increased the prevalence of hyperglycemia.MHO,obese abnormal metabolic increased the pevalence of NAFLD.Hypertension and hyperlipidemia did not increase between different obese subtypes.