Clinical Study Of Jieyu Anshen Decoction In Treating Essential Hypertension With Anxiety

Objective To clarify the efficacy of Jieyu Anshen decoction in improving anxiety symptoms and lowering blood pressure in patients with essential hypertension and anxiety.To explore the principle of prescription and provide a new way of thinking for the treatment of this kind of diseases with traditional Chinese medicine.Methods In this study,60 patients with essential hypertension with anxiety were randomly assigned to the treatment group and the control group.The treatment group was treated with Jieyu Anshen decoction and the control group was treated with tandoxone citrate for 4weeks.Before and after treatment,the general status of the patients wasrecorded,and four times of blood pressure before and after treatment were recorded respectively.The scores of SAS/SDSs were recorded before and after treatment.The circadian rhythm of blood pressure was recorded 24 hours after treatment,and the symptoms of stagnation of qi and debilitating fire in traditional Chinese medicine were also recorded.After treatment,SPSS22.0 was used to analyze the data.Results On the basis of the effectiveness of anti-anxiety therapy,the total effective rate of antihypertensive therapy was 70% in the treatment group,80% in the control group and no significant difference between the two groups(P> 0.05),4 cases in the treatment group and5 cases in the control group.It was concluded that antianxiety therapy was effective on the basis of effective antihypertensive therapy,which indicated that the two groups had the same antihypertensive effect.Before and after treatment,the standard score of SAS/SDS in both groups decreased significantly(P>0.05),the scores of systolic / diastolic blood pressure(SBP)and diastolic blood pressure(DBP)decreased significantly(P> 0.05),and the scores of systolic/diastolic blood pressure decreased(P > 0.05).The effective rate of blood pressure circadian rhythm was 36.6 % in the treatment group,30% in the control group and no significant difference in the effective rate between the two groups(P > 0.05),indicating that both groups could improve the scores of systolic blood pressure,diastolic blood pressure and anxiety.There was no difference between depression score and circadian rhythm of blood pressure.In the treatment group,the effective rate of improving the symptoms of stagnation of qi and stagnation of fire in TCM was 93.3%and that in the control group was 70%.The difference between the two groups was statistically significant(P < 0.05),which suggested that the treatment group was superior to the control group in improving such symptoms.Conclusion On the basis of effective anti anxiety therapy,Jieyu Anshen Decoction has a reliable effect on lowering blood pressure,and it can obviously improve the symptoms,safety and nontoxic side effects of the stagnation of depression in this kind of Chinese medicine.Clinical can refer to the thinking of relieving depression and tranquilizing the mind of such patients dialectical treatment.