The Diagnostic Yield Of Endoscopic Ultrasound Guided Fine Needle Aspiration For Pancreatic Tumors

Objective:To evaluate the diagnostic yield of Endoscopic ultrasound guided fine needle aspiration(EUS-FNA)for pancreatic tumors.Methods:By retrieving the digestive endoscopy database of The Second Hospital of Hebei Medical University,screening a total of 15 patients(9 men,6 women,age from 33 to 80)operated by endoscopic ultrasonography from September 2015 to December 2017.These patients were diagnosed as suspicious lesions of pancreas by ultrasound,CT or MRI.The puncture samples of all patients were processed by liquid-based cytology,histopathology or smears.The cystic fluid of pancreatic cystic lesions were sent tumor markers detection.Final diagnosis were based on histological or cytological evidence or on follow-up.Results:All these 15 patients with pancreatic tumors were detected by EUS,and the diagnosis were made in 11 cases of positive pathological results.4 cases of negative results.The overall diagnosis sensitivity,specificity and accuracy of EUS-FNA for distinguishing malignancy from benign lesions of pancreas were respectively 84.6%,100%,73.3%.The diagnostic accuracy of EUS-FNA with ?3 passes was consistent with >3 passes.After EUS-FNA,3 patients developed acute mild pancreatitis,and recovered soon following the treatment.Conclusions:Our experience confirms that EUS-FNA was a safe and accurate diagnostic method for distinguishing malignancy from benign lesions of pancreas with rare complications.