A Clinical Study Of Keningheji Treat Cough Variant Asthma

Objective:This study observed and evaluated the effectiveness and safety of useing keningheji to treat the cough variant asthma,and provide clinical basis for the treatment of CVA with keningheji.Methods:There are 79 CVA patients who meet the conditions for enrollment.They come fromrespiratory Clinic of Mianyang Traditional Chinese Medicine Hospital and Yanting Traditional Chinese Medicine Hospital or cough specialist clinic raditional Chinese Medicineof Jiangyou Hospita.The cases were randomly divided into two groups,39 patients of them took A(20ml,tid),and another 40 patients took Suhuangzhike Capsule(3 tablets,tid)to treat CVA.1 week for a course of treatment,a total of 2 courses.In the course of treatment,We will record the patient’s condition in detail and fill Visual Analogue Scale(VAS),cough Score,the main symptom score,the minor symptom score,and the safety indicator table.After treatment,we use SPSS21.0 statistical analysis of the observations.Result:1.Before treatment,baseline levels such as gender,age,and BMI in both groups of patients were statistically analyzed,the results showed no significant difference(P>0.05).2.Before treatment,there was no significant difference in indicators of VAS,cough Score,the main symptom score,the minor symptom score,P>0.05,Which shows that there was no significant difference in the degree of coughing,coughing frequency,concomitant symptoms.3.There was a significant difference inscores of VAS,cough Score,the main symptom score,the minor symptom before and after treatment between the two groups(P<0.01).4.After the end of treatment,the Wilcoxon signed-rank test was used to compare the two groups,P<0.05,which was statistically significant.5.Comparing the Integral difference of VAS,cough Score,the main symptom score,the minor symptom between the two groups before and after treatment,the Integral difference of cough Score was statistical significance,P=0.043<0.05;while the rest did not have statistical significance,P>0.05.6.Comparing total effective:Comparing the effectiveness of the two groups in the treatment of cough,coughing frequency,concomitant symptoms,the chi-square test results were P>0.05 without statistical significance.7.No adverse reactions occurred in both groups during the treatment.Conclusion:Efficiency of the keningheji group was 92.30% and markedly effective rate of 76.92%,as well as efficiency of the Suhuangzhike Capsule group was 90.00% and markedly effective rate of 67.50% in the treatment of CVA.The two groups of results were treated with chi-square test,P>0.05,It suggests that the efficacy of keningheji is similar to Suhuangzhike Capsule in treatment of CVA,and no adverse reactions.It is worthy of clinical promotion because of its positive effects and high safety.