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Prevention And Treatment Of Postsurgical Gastroparesis Syndrome After Pancreaticoduodenectomy

Posted on:2020-11-21Degree:MasterType:Thesis
Country:ChinaCandidate:J C LiangFull Text:PDF
GTID:2404330572475473Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective:The purpose of this paper is to explore the influencing factors of gastric spastic syndrome(PGS)after pancreaticoduodenectomy(PD),and to propose corresponding treatment methods and preventive measures for patients with PGS,and provide reference for future treatment and prevention of PGS.Methods:Selected from January 2008 to March 2019 during pancreatic duodenal resection patients,according to the inclusion criteria,157 patients were involved in the research,according to whether the stomach after collapsing into PGS and the PGS groups,the patients’ age,gender,preoperative high bilirubin,operation time,surgical procedure,intraoperative blood loss,postoperative hyperglycemia,low serum albumin leels after operation,postoperative complications(intraperitoneal hemorrhage,gastrointestinal bleeding,biliary fistula,pancreatic fistula,intestinal fistula),and so on and so forth,using SPSS analysis software,to analyze the data,Univariate Logistic multivariate analysis was performed to determine the risk factors of postoperative gastroparesis.Results:Gastroparesis occurred in 21 of the 157 patients,with an incidence of 13.3%.Two groups of patients in gender,intraoperative blood loss,postoperative hyperglycemia,postoperative abdominal gastrointestinal anastomosis way,stomach bleeding,postoperative gastrointestinal bleeding,there was no statistically significant difference,etc,in the age,operation time,surgical procedure,postoperative complications(biliary fistula,pancreatic fistula,intestinal fistula)and postoperative medication data differences have statistical significance.Multivariate analysis showed that age(>60 years),postoperative hypoalbuminemia(<30g/L),postoperative complications(biliary fistula,pancreatic fistula,intestinal fistula)belonged to the stomach after pancreaticoduodenectomy Risk factors for sputum syndrome(0R>1,P<0.05),and the use of modified surgical methods was a protective factor for postoperative gastroparesis syndrome(OR<1,P<0.05).Conclusions:1.Once PGS occurs,more conservative treatment,fasting,nutritional support,use of gastrointestinal motility drugs,Chinese medicine treatment and other non-surgical methods,most of which can be effectively cured.2.Maintain albumin levels above 30g/L after surgery,reduce postoperative complications(biliary fistula,pancreatic fistula,intestinal fistula),which can effectively prevent the occurrence of PGS.3.The use of improved surgical methods can reduce the incidence of PGS.3.The use of improved surgical methods can reduce the incidence of PGS.
Keywords/Search Tags:pancreatoduodenectomy, postsurgical gastroparesis syndrome, risk factors, prevention, treatment
PDF Full Text Request
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