| Objective: cervical cancer is the world's third largest female cancer killer,but cervical cancer is a better cancer,to achieve the best therapeutic effect,depends on the perfect cooperation of patients and good treatment plan.Brachytherapy plays an important role in the treatment of cervical cancer.For the treatment of locally advanced cervical cancer patients with brachytherapy,intracavitary combined with interstitial interstitial radiotherapy and traditional three-channel post-operative radiotherapy(uterine tube +oval pair)are two common methods of intracavitary radiotherapy.28 cases of this study by comparing the center approved by pathology diagnosed with locally advanced cervical cancer patients with the unarmed tissue inserted between plant intracavitary radiotherapy(IC/ISBT including uterine tube combined with A metal needle source applicator,through the guidance of three-dimensional CT combined with clinical examination of department of gynaecology,the unarmed freedom's joint cavity insert metal needle inserted between the radiation graft)and traditional brachytherapy(ICBT)of point A dose(A1,A2),HR CTV D90,HR CTV D100,endanger organs(bladder,colon,rectum,small intestine)dosimetry difference and the recent curative effect.In order to find a newer,more effective and more convenient treatment technology for clinicians in the close treatment of cervical cancer.Methods: clinical data of 28 patients with locally advanced cervical cancer who were admitted to the second affiliated hospital of dalian medical university from May 2018 to December 2018 and were clearly diagnosed as locally advanced cervical cancerthrough pathology through IC/ISBT or ICBT treatment were collected and retrospectively analyzed,including 12 patients who were treated with IC/ISBT at the same time and 16 patients who were treated with ICBT alone.SPSS17 was used for all data in this study.Point A dose(A1,A2),target dose(HR CTV D90,HR CTV D100),and organ at risk(bladder,rectum,sigmoid colon,small intestine D2 cc,do.1cc)of the two treatment methods were compared by the software.Result: 1.Target area dose comparison: compared with the traditional three-way radiotherapy alone,the dose at point A was significantly increased(A1 on the right side and A2 on the left side)with the combination of unarmed tissue interposition and intracavitary radiotherapy,and the difference between the two treatment methods was statistically significant(P= 0.00).In the clinical target dose(HRCTV D90 and HRCTV D100)of freehand intertissue interposition combined with intracavitary radiotherapy was significantly higher than that of traditional three-way post-loading therapy,and the difference between the two treatment methods was statistically significant(P= 0.00).2.Comparison of irradiation doses to organs at risk(OARs): in the combination of freehand interstitial implantation and intracavitary radiotherapy,D2 cc and D0.1cc were performed for organs at risk(bladder,rectum,colon and small intestine).There was no statistically significant difference between the dose of 1cc and the traditional 3-channel loading therapy alone(P> 0.05).3.Comparison of short-term efficacy(1 month after the close treatment): there was no statistically significant difference between the short-term efficacy of freehand intertissue interposition combined with intracavitary radiotherapy and the short-term efficacy of the traditional three-way simple postoperative therapy one month after the treatment(P> 0.05).Conclusion: In locally advanced cervical cancer after close treatment,guided by CT combined with clinical examination of department of gynaecology of unarmed organization between metal needle plant of uterine cavity tube joint cavity radiation therapy compared with traditional three-channel cavity radiation,interstitial plugged into joint cavity radiation graft without any increase in endanger the exposure dose of organs and reduce in the near future curative effect(close to 1 month after treatment)at the same time,can obviously improve patients with high-risk target dose,dose of A point,can effectively prevent palace caused by low dose by local recurrence,has relatively obvious advantage.It is a newer,more effective and more convenient treatment technology for clinicians in the close treatment of cervical cancer. |
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