Analysis Of Correlative Factors Of Cervical Lymph Node Metastasis In Papillary Thyroid Microcarcinoma Patients In A Hospital In Qiqihar

Objective:Papillary thyroid microcarcinoma(PTMC)is a papillary thyroid carcinoma with a diameter of less than 1.0 cm.The main reasons for the increase of papillary microcarcinoma are radiation,diet,tertiary prevention(emphasis on physical examination,color Doppler ultrasound equipment),and the improvement of diagnostic level(fine-needle aspiration cytology,genetic testing).PTMC nodules are small in size,slow in growth,and are far less harmful to the human body than other organs of malignant tumors,but some of them are more aggressive,early cervical lymph node metastasis(CLNM),increasing the risk of distant metastasis or local recurrence of PTMC.There is no standard guideline for the extent of primary resection and neck lymph node dissection for PTMC requiring surgical resection.In this paper,the correlation between thyroid micropapillary carcinoma(PTMC)and cervical lymph node metastasis(CLNM)were analyzed,and the value of ultrasound in the diagnosis of PTMC was discussed.Methods:The clinical data of 381 cases of patients who underwent thyroid color doppler ultrasound examination and were confirmed as PTMC by postoperative pathology in a first-grade hospital in Qiqihar from January 2014 to December 2017 were collected.The patient's sex,age,ultrasonographic and clinical features were recorded.SPSS 22.0 was used for data analysis.For the description of measurement data,mean ± standard deviation(SX ±)was used.For description of the count data,the adoption rate and composition ratio(%)were used.To compare the characteristics of patients with cervical lymph node metastasis,single factor analysis was performed using chi-square test.With P < 0.05 as the standard,statistically significant single factor variables were included in the multiple Logistic regression model to analyze the influencing factors of CLNM in PTMC patients.Results:1.Among the 381 patients with PTMC,100 were males,accounting for 26.2%,while 281 were female cases,accounting for 73.8%.The age range is from 18 to 71 years,the average age is 38.9 ± 10.2 years.There were 188 cases of cervical lymph node metastasis,and 193 cases had no metastasis,and the cervical lymph node metastasis rate was 49.3%.2.Univariate analysis showed that there were statistically significant differences in age,tumor side differences,number,morphology,boundary,calcification size and total diameter of PTMC patients with cervical lymphatic metastasis(P < 0.05).3.Multivariate analysis showed that age,tumor profile,morphology,calcification lesion size and total diameter were independent risk factors for cervical lymph node metastasis in PTMC patients(P < 0.05).Conclusions:1.The incidence of cervical lymph node metastasis in PTMC patients was 49.3%.2.The age of the patients was less than 45 years,and cervical lymph node metastasis was easy to occur in bilateral glands of tumor nodules.3.The irregular shape of the tumor,the existence of calcified foci(mainly small calcification)and the large diameter of tumor nodules are the risk factors of cervical lymph node metastasis in PTMC.These ultrasound features may be helpful in indicating the risk of cervical lymph node metastasis.To help patients develop surgical procedures.