Clinical Significance Of Heterotopic Gastric Mucosa Of The Upper Esophagus And The Factors Of Affecting Detection

OBJECTIVE:To analyze the clinical significance of heterotopic gastric mucosa of the upper esophagus and to explore the related factors affecting the endoscopic detection rate of the disease.METHODS:The study population consisted of patients seen in Handan City First Hospital from May 2018 to February 2019.Patients should be inquiried according to the questionnaire before gastroscopy,and recorded endoscopist,gastroscopy approach,gastroscopy mode,clinical manifestations and pathological findings.RESULTS:3070 patients were enrolled into the study.Among them,129 cases were HGMUE.The rate of endoscopic detection was determined as 4.2%.The number of cases detected and the detection rate of HGMUE among the groups are as follows:56 cases of traditional gastroscopy group(2.8%),88cases of painless gastroscopy group(7.1%),72 cases of NBI group(5.9%),57cases of conventional images group(3.3%),78 cases of the endoscopist was informed of the subject group(5.7%),51 cases of the endoscopist was not informed of the subject group(3.0%),11 cases of 0-2 years experience group(1.5%),45 cases of 3-7 years experience group(3.6%),73 cases of 8 years experience and above group(6.8%).gastroscopy approach,gastroscopy mode,awareness and experience of the endoscopist have an impact on the endoscopic detection rate of HGMUE by statistical analysis.Clinical manifestations included in the statistics:24 cases of heartburn(26.37%),8 cases of regurgitation(8.79%),1 case of abdominal pain(1.10%),30 cases of Globus pharyngeus(32.97%),2 cases of dysphagia(2.20%),34 Cases of continuous throat clearing(37.36%),20 cases of chronic cough(21.98%),1 case of sore hoarseness or vocal dysfunction(1.10%),27 cases of cough after a meal or after lying down(29.67%)and 10 cases sputum or nasal reflux(10.99%).Logistic regression analysis showed that globus pharyngeus,continuous throat clearing,chronic cough and cough after a meal or after lying down were related to HGMUE.Conclusions:1.The endoscopic detection rate of HGMUE is related to gastroscopy approach,gastroscopy mode,awareness and experience of the endoscopist.Painless gastroscopy,NBI and awareness and experience of the endoscopist increased can significantly improve the endoscopic detection rate of HGMUE.2.Symptoms associated with HGMUE include globus pharyngeus,continuous throat clearing,chronic cough and cough after a meal or after lying down.