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Using Multi-slice CT To Investigate The Correlation Between Splenorenal Shunt And Clinical Features In Patients With Liver Cirrhosis

Posted on:2020-02-03Degree:MasterType:Thesis
Country:ChinaCandidate:S ZhanFull Text:PDF
GTID:2404330575479936Subject:Master of Clinical Medicine
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Objective: In these patients with liver cirrhosis,we discussed the relationship between liver function,biochemical indexes and clinical complications and splenorenal shunt(SRS)?the ratio of splenorenal shunt(SRS)to portal vein(PV),and SRS/PV grouping(<1 group and ?1 group).Methods: This paper collected 280 patients with liver cirrhosis in our hospital,who underwent MSCT and had sufficient clinical data,including 137 case with SRS?147 cases without SRS.We retrospectively analyzed biochemical indicators and clinical complications(including gastrointestinal bleeding,portal venous system thrombosis,hepatic encephalopathy,esophageal varices and ascites),and through MSCT imaging,we measured SRS?SRS/PV and the group of SRS/PV(<1 group and?1 group).We used SSPS 22.0 software to analyze the relationship of these data,and to provide more information for clinical and predict the occurrence of complications.Results: 1?The diameter of portal vein?left gastric vein of cirrhosis patients with SRS was significantly smaller than patients without SRS;The incidence of hepatic encephalopathy in patients with SRS was significantly higher than patients without SRS in liver cirrhosis.2?There were significant statistical differences in SRS diameter,SRS/PV ratio and SRS/PV grouping between different CHILD classification(p<0.01).The SRS diameter and SRS/PV ratio of grade C were significantly higher than group g and g(p < 0.01).In the group of SRS/PV?1,the patient of group C were significantly more than those of group g.3?The diameter of SRS was positively correlated with left gastric vein and splenic vein.In this study,the SRS/PV ratio did not affect the size of the internal diameter of the portal venous system,but the diameter of the superior mesenteric vein in the SRS/PV?1 group was less than that in the SRS/PV<1 group(P=0.033).4?There was a positive correlation between prothrombin time(PT)?alkaline phosphatase(g LP)and SRS/PV,albumin(glb)?cholinesterase(CHE)and SRS/PV were negatively correlated.5?The diameter of SRS diameter and SRS/PV in the group with hepatic encephalopathy were significantly larger than the group with non-hepatic encephalopathy(P=0.008,P=0.002).The incidence of hepatic encephalopathy in group of SRS/PV?1 was higher than the group of SRS/PV<1(P=0.007),therefore the hepatic encephalopathy should be alert when the diameter of SRS is larger than PV.6?The diameter of SRS,the ratio of SRS/PV ratio and SRS/PV grouping showed no significant difference in the incidence of gastrointestinal bleeding and venous thrombosis.7?There were not statistically different with the severity of esophageal varicose veins and SRS diameter,SRS/PV ratio,SRS/PV grouping.gut when gastrointestinal bleeding was excluded,there were significant differences in SRS diameter among different severity grades of esophageal varicose vein,the diameter of SRS of grade 1 was higher than that of grade 2 in patients with esophageal varicose veins(P=0.030).8?There were statistically significant differences between the groups of ascites severity and the diameter of SRS diameter?the ratio of SRS/PV?SRS/PV grouping.and there were significant differences between SRS diameter and the groups of ascites severity.The diameter of SRS in patients with a large number of ascites of patients was significantly larger than patients without ascites(P=0.008)and with a small amount of ascites(P=0.014).Conclusions: CT is one of the important examinations for patients with liver cirrhosis.The measurement of SRS diameter on CT is very simple and direct.To evaluate the relationship between SRS diameter,SRS/PV and liver function grading,clinical biochemical indicators and complications can provide more information for clinical,and play an important role in the prediction of complications.
Keywords/Search Tags:X ray computer, Multilayer computed tomography, Cirrhosis of the liver, Splenorenal shunt, Hepatic encephalopathy
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