Discussion On TCM Syndrome Of Fever After Neurosurgery Based On Cluster Analysis And Factor Analysis

Objective:This study screened patients who were hospitalized in neurosurgery from Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2015 to September 2018.,including patients who meet the inclusion criteria to explore the characteristics of TCM syndromes of fever after neurosurgery to lay the foundation for the preliminary development of clinically operative and operative TCM syndrome diagnostic criteria.Methods:This study uses a combination of literature research and clinical retrospective research,using mathematical statistics methods to prepare a four-diagnosis information collection table for fever and TCM syndromes after craniocerebral surgery,establishing a database,using SPSS22.O statistical software,and using descriptive analysis.The methods of frequency analysis,factor analysis and cluster analysis were used to investigate the TCM syndromes of fever after neurosurgery,and the classification criteria for the service clinical purpose were preliminarily established.Results:(1)Literature research:28 articles in accordance with the inclusion criteria were included,and 15 different syndromes were sorted out as follows:dampness and heat syndrome(15 cases),yin deficiency fever syndrome(12 cases),and LiReChiSheng syndrome(12)Case),Qi deficiency fever s\rndrome(11 cases),blood stasis syndrome(7 cases),hot admission blood syndrome(5 cases),phlegm heat syndrome(5 cases),blood deficiency syndrome(3 cases),Sputum stagnation syndrome(3 cases),food stagnation and heat syndrome(3 cases),Shaoyang and Yangming syndrome(1 case),cold and dampness syndrome(1 case),liver yang stagnation syndrome(1 case),yang deficiency fever syndrome(1 case),qi stagnation fever syndrome(1 case).(2)Statistical and standardized analysis of the syndrome descriptions contained in the literature,according to the,Guidelines for Clinical Research of New Drugs in Traditional Chinese Medicine",the 50 symptoms selected are assigned according to the presence or absence,The score without symptoms is 0,and the symptomatic score is 1-3 according to the severity of the disease(Among them,the pathological records of the tongue and vein are missing due to objective factors such as orotracheal intubation,invasive arterial pressure detection,and patient coma,are not included in the final statistics.).(3)Clinical research:250 patients with fever after neurosurgery were enrolled,and a database of clinical symptoms and signs was collected.Through factor analysis,12 common factors in accordance with TCM syndrome diagnosis were obtained,and the brain reflected in the literature The basic pathogenesis of postoperative fever is the same.150 patients were clustered with the common factor as the independent variable,and repeated verification.Finally,the expert group discussed the syndrome types that conformed to the traditional Chinese medicine theory,and the distribution was as follows:Yangming viscera syndrome(57 cases),hot entry blood syndrome(35 cases),yin deficiency and exogenous invasion syndrome(112 cases),liver spleen deficiency syndrome(27 cases),phlegm heat disturbing consciousness syndrome(19 cases).The distribution law is basically consistent with the etiology and pathogenesis reflected by the factors,which reflects the basic pathogenesis of fever after neurosurgery.Conclusion:The introduction of mathematical statistics method into the TCM syndrome standard of fever after craniocerebral surgery reflects the new model of TCM theoretical research introducing modern scientific research methods,and provides a relatively objective and systematic method for clinical dialectical treatment of postoperative fever of craniocerebral operation.Dialectical reference.