Analysis Of Factors Influencing The Five-year Survival Rate And Prognosis Of Patients With Stage ?b-?a Cervical Cancer

OBJECTIVE: By retrospectively collecting 136 clinical stages(also known as FIGO stage,Federation International of Gynecology and Obsterics)in our hospital,this article aims to count the five-year survival rate and analyze what influences that the facts of clinical and pathology have on the prognosis,it also provides a basis for improving the quality of life of patients with cervical cancer in our hospital and improving the prognosis of patients with cervical cancer in our hospital.METHODS: A total of 136 patients with cervical cancer who saw a doctor in the First Affiliated Hospital of Hebei North University(a comprehensive tertiary hospital)from January 2009 to December 2013 were enrolled.The FIGO(clinical)stage of the selected patients was?b-?a Stage,and all underwent radical resection of cervical cancer(wide uterus + pelvic lymphadenectomy).Follow-up work was conducted by outpatient review,telephone,WeChat,etc.The deadline of Follow-up work was December 31,2018.Establish a database to record all patients' information,including age,birth times,FIGO stage,tumor size(diameter),pathological type,tumor differentiation,Muscle infiltration depth,Lymph vascular space invasion,lymph node metastasis,retention of ovaries or not,postoperative Adjuvant therapy,etc.Count the five-year survival rate and analyze what influences that the facts of clinical and pathology have on the prognosis after making a call to all the patients.Data statistics were taken using an excel worksheet and statistical analysis was performed using SPSS 22.0.The survival time was from the first day after surgery to the end of follow-up or the day of death due to cervical cancer(in months).The survival rate was calculated by Kaplan-Meier method.A univariate analysis of the influence of clinical,pathological factors on prognosis was performed by log-rank test.The multivariate analysis was performed by COX risk regression model.P<0.05 was considered statistically significant.RESULTS: Of the 136 patients,17 died,with a overall five-year survival rate of 97%.Univariate analysis showed that tumor size(diameter),pathological type,depth of myometrial invasion,LVSI,and lymph node metastasis were statistically significant to patients with stag?b-?a cervical cancer(P<0.05);however,Age,parity,FIGO(clinical)stage,degree of tumor differentiation,postoperative adjuvant therapy,and whether or not the ovary was preserved had no significant effect on the prognosis of patients with stage ? b-? a cervical cancer(P>0.05).Multivariate analysis showed that pathological type,depth of myometrial invasion and lymph node metastasis were independent risk factors for prognosis of patients with stage Ib-IIa cervical cancer(P <0.05).CONCLUSION:Among the patients with Ib-IIa cervical cancer in my hospital,those who are 46-50 years old have a high incidence of the disease;The overall five-year survival rate was 97% after operation;The multivariate analysis showed that pathological type,depth of myometrial invasion,and lymph node metastasis were Independent risk factors for prognosis in patients with stage Ib-IIa cervical cancer.