| Objective To explore the clinical application value of magnetically guided capsule endoscope(MGCE)in the diagnosis of upper digestive tract diseases,the feasibility,safety,tolerance,detection of disease and several factors influencing the time of capsule passing through esophagus were analyzed.Methods In March 2017-March 2018 in our hospital digests medical MGCE examination of 60 cases of patients with upper gastrointestinal symptoms,client basic information collection,record and analyze MGCE main anatomical structure of the image acquisition of the stomach,capsule by lesions found in the esophagus,stomach,time situation,capsule eduction,psychological activities before and after the check,adverse reactions occurred and postoperative satisfaction.The detection rate,positive predictive value,negative predictive value,sensitivity and specificity of MGCE in gastric focal lesions were observed.Results 1.The completion rates of cardia,fundus,body,Angle,sinus and pylorus were 85.00%,88.33%,100.00%,95.00%,98.33% and 100.00%,respectively.The visual condition of gastric mucosa was good,accounting for 96.67% of the 60 cases.2.The 60 patients were divided into two groups according to their age 60 years old and age <60 years old,among which 28 patients were aged 60 years old.The average time of capsules passing through the esophagus was(61.93±61.03)seconds,and 32 patients were aged <60 years old.The average time of capsules passing through the esophagus was(76.00±72.04)seconds.According to body mass index,the patients were divided into three groups,that is,BMI<18.5,BMI18.5-24,and BMI>24.The rank-sum test was used for comparison among multiple groups,P=0.383(P>0.05).There was no significant difference in esophageal passage time between the three groups3.60 cases subjects found that patients with upper gastrointestinal lesions in 43 cases,positive diagnostic rate was 71.67%(43/60),upper gastrointestinal lesions found 56 times,esophagitis,4 cases(7.14%),28 cases(50.00%),erosive gastritis of chronic superficial gastritis with bile regurgitation in 2 cases(3.57%),cardiac inflammation in 2 cases(3.57%),7 cases(12.50%),gastric polyp gastric ulcer in 1case(1.79%),duodenal bulb inflammation in 7 cases(12.50%),duodenal ulcer in 5cases(8.93%).4.Gastroscopy was performed in 30 patients within 4 weeks before and after examination,and the results were consistent in 27 patients(the consistency rate was90.00%(27/30)).There were 3 inconsistency cases,one of which showed gastric antrum ulcer under MGCE,and the gastroscopy showed normal.Two cases showed gastric polyps under gastroscope,but no lesion was found under MGCE.The positive rate of local lesions detected by gastroscopy was 33.33%(10/30),and the positive rate of MGCE for gastric lesions was 30.00%(9/30),with no statistically significant difference between the two(P>0.05).The sensitivity,specificity,positive predictive value and negative predictive value of MGCE were 80.00%,95.00%,88.89% and90.48%,respectively.5.All the 60 patients successfully completed the MGCE examination,and 58patients(96.67%)were free from any discomfort during the examination.The satisfaction of subjects receiving MGCE examination was 98.33%,and that of gastroscopy examination was 6.67%,significantly higher than that of gastroscopy examination.Conclusion MGCE has a high detection rate for upper gastrointestinal diseases,and the examination process is safe,non-invasive and controllable,which can be used for the examination of upper gastrointestinal diseases. |
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