The Basic Principle Of ASL Technology And Its Research Progress In Vascular Cognitive Impairment

Vascular cognitive impairment(VCI)is a group of syndromes ranging from mild cognitive impairment to dementia.As a functional magnetic resonance imaging(fMRI)technique,arterial spin labeling(ASL)can mark the cerebral blood of VCI patients at various stages without relying on the blood-brain barrier by marking the hydrogen protons in arterial blood with specific pulses.Flow rate(CBF)with good time resolution has become an important imaging tool for diagnosis and follow-up of VCI.This paper reviews the basic principles of ASL technology and the research progress in VCI in recent years.