Efficacy And Safety Of Ultrasound-guided Percutaneous Microwave Ablation For Small Hepatocellular Carcinoma In Special Parts

Objective: To evaluate the clinical efficacy and safety of ultrasound-guided percutaneous microwave ablation for small hepatocellular carcinoma in special parts.Methods: A retrospective analysis of the clinical data of 121 patients undergoing ultrasound-guided percutaneous microwave ablation in our hospital from February 2014 to December 2017,including 69 patients with small hepatocellular carcinoma in special parts,a total of 75 ? 3cm lesions;52 patients with primary small hepatocellular carcinoma in non-special parts,a total of 57 ? 3cm lesions.All patients signed informed consent and met medical ethics requirements.According to the patient's imaging,laboratory results and clinical manifestations,the single complete ablation rate,local control rate,intrahepatic recurrence rate,total recurrence rate,AFP decrease rate,and the incidence of complications were compared between the two groups,as well as the specific complications of the two groups of patients after receiving ablation.Results:The single complete ablation rate of hepatocellular carcinoma lesions in the special and non-specialized parts were evaluated by ultrasound-guided one-month after percutaneous microwave ablation: 92%(69/75)and 94.7%(54/57);The local control rates at 6 months,1 year,and 2 years after ablation of the special and non-specialized parts were: 96.0%(72/75),89.3%(67/75),86.6%(65/75),and 98.2%.(56/57),94.7%(54/57),93.0%(53/57),the intrahepatic recurrence rates at 6 months,1 year,and 2 years after ablation of the special and non-specialized parts were: 14.5%(10/69),20.3%(14/69),23.2%(16/69)and 11.5%(6/52),15.4%(8/52),17.3%(9/52);The total recurrence rates in the last 2 years were: 37.7%(26/69)and 25.0%(13/52).The decline rates of AFP after 3 months were 52.3% and 67.7%,respectively.The complication rates were: 39.1.%(27/69)and 25.0%(13/52),there was no significant difference between the two groups(P>0.05).Conclusion: The ultrasound-guided percutaneous microwave ablation is safe and effective in the treatment of small hepatocellular carcinoma in special parts.The curative effect is similar to that of small hepatocellular carcinoma in non-specialized parts.There is no difference in complications between the two groups after ablation.