Analysis Of The Efficacy Of Indocyanine Green Angiography For Intracranial Aneurysm Clipping

Objective:Surgical intervention for intracranial aneurysm has two standard treatment means were endovascular embolization aneurysm and craniotomy for aneurysm clipping under the microscope.The location of the intracranial aneurysm is complicated,with numbers of perforating vessels and extremely high variability.Therefore,most neurosurgeons mainly use craniotomy for aneurysm clipping under the microscope at home and abroad.For the past few years,the indocyanine green angiography(ICGA)assistive technique can be used to gather real time information of intravascular blood flow.But on whether the technique can reduce postoperative complications and improve prognosis.There are few related research reports at home and abroad..We retrospectively compared whether the efficacy of intraoperative ICGA craniotomy was superior to that of traditional craniotomy.Methods:The data of 90 patients with intracranial aneurysms admitted to our hospital from January 2015 to October 2017 were retrospectively analyzed and divided into observation group(n=44)and control group(n=46).The observation group was treated with IGCA technique under the microscope for aneurysm clipping,while the control group was treated with microscopic aneurysm clipping.Were recorded age,gender,Hunt-Hess classification,the position and shape of the aneurysm(bleeding).Record the results of the treatment of patients with aneurysm remnant.and cerebral infarction,were recorded operative time,hospital stay,intraoperative blood loss.Postoperative follow up results of the difference was assumed to be statistically significant when(P < 0.05).The modified Rankin scale were compared at 12 months postoperative.Results:The CTA/DSA observations were performed after operation.The average operation time of the observation group and the control group were 181.4±28.1 min and 175.0±29.2 min.The average intraoperative blood loss were 235.4±85.3 ml and 257.5±63.6 ml.So the difference was not statistically significant(P>0.05).There were statistical differences in the hospital stay between the observation group and the control group were 18.8±2.4 days and 22.1±1.9 days.The difference was statistically significant(P<0.05),The observation group's postoperative aneurysm remnant have 2 cases and the control group have 11 cases,The observation group's cerebral ifarction have 3 cases and the control group have 14 cases.The difference was statistically significant(P<0.05),The independent survival rate of the modified Rankin scale was significantly higher in the observation group than that in the control group 12 months postoperative.Conclusion:Compared with conventional intracranial aneurysm craniotomy,intraoperative ICGA technique can significantly reduce the incidence of postoperative aneurysm remnant and cerebral infarction..Also can shorten hospital stay and improve long-term Prognosis.Moreover,ICGA is cheaper,less time consuming to operate,and can be operated multiple times with high accuracy.Therefore,ICGA angiography has a wide application prospect in surgery,which is suitable for most hospitals.