Clinical Observation On The Treatment Of Early Diabetic Nephropathy Based On "Syndrome Differentiation And Treatment"

Objective In order to give full play to the advantages of "syndrome differentiation and treatment",this method was used to evaluate the improvement of clinical symptoms and signs of patients with early Diabetic Nephropathy,as well as the effect on early urinary microalbumin.Patients who met the diagnostic criteria of traditional Chinese and western medicine for Diabetic Nephropathy and the inclusion and exclusion criteria were divided into three groups for comparative study,so as to objectively evaluate the effectiveness and safety of this treatment for early DN.At the same time,the common clinical syndromes of early DN were summarized,so as to obtain accurate and effective treatment methods and guide clinical practice.Method In the case of the early DN and the criteria for the diagnosis of western medical treatment and the inclusion of the criteria for the elimination of the criteria,there are 40 cases of "syndrome differentiation and treatment" group,40 in the Chinese patent medicine group,and 40 in the black group.All patients in the three groups were given low-salt,low-fat and low-protein diet,oral drugs or insulin to control blood glucose,and ACEI or ARB to control blood pressure and other basic therapies.The treatment group adopted "syndrome differentiation for treatment" method by this basic,which selected Chinese medicine with the 2 months treatment period.The Chinese patent medicine group was treated with Huangkui Capsule at the same time.The blank group received only basic treatment.The last,the indicators before and after treatment were observed and recorded.Results 1 After treatment,FBG and 2hPBG of the three groups were controlled within the normal range(p<0.05).The degree of blood glucose in the "syndrome differentiation and treatment" group was better than that in the Chinese patent medicine group and the blank group(p<0.05).There was no significant difference in blood glucose between the Chinesepatent medicine group and the blank group after treatment(p>0.05).And liver function and kidney function maintained normal range before and after treatment(p>0.05).2 There were statistically significant differences in urinary microalbumin levels before and after treatment(p<0.05).After treatment,there were statistically significant differences between the "syndrome differentiation and treatment" group and the Chinese patent medicine group(p<0.05);The difference between "syndrome differentiation and treatment" group and blank group was statistically significant,too.3 The symptoms of three groups before and after treatment had achieved a certain degree of efficacy.The efficacy of the "syndrome differentiation and treatment" group(97.5%)was significantly better than that of the Chinese patent medicine group(62.5%)and the blank group(17.2%),and the Chinese patent medicine group was better than the blank group.Conclusion 1 The "syndrome differentiation and treatment" method is better than the traditional Chinese medicine Huangkui Capsule in the treatment of urinary microalbumin and reducing the Chinese medicine symptoms.2 The "syndrome differentiation for treatment" method can reduce the patient’s blood glucose and make it control more stable.3 The "syndrome differentiation and treatment" method in the treatment of early Diabetic Nephropathy is more safe and reliable and should be widely promoted in clinical.4 The blood glucose control stablly can also reduce the urinary microalbumin at a certain level,which can alleviate the symptoms of traditional Chinese medicine,too.