| Objective:With Essential hyPertension(EH)patients in the community as the research object,the differences in the efficacy of moxibustion sensitivity,moxibustion dose and moxibustion effect were observed through the heat-sensitive moxibustion intervention,so as to provide a scientific basis for the moxibustion community intervention model.Methods:A total of 104 EH patients who all in a set of acupoints(fengfu,dazhui and double side yongquan)are suspended moxibustion in heat-sensitive moxibustion,probing 3 times,1 time/day.According to the heat-sensitive moxibustion feeling and a bit of feeling the frequency,All patients above are divided into heat-sensitive group(three acupoints in at least one aperture a heat-sensitive moxibustion sensation of a frequency of 2 days or more)and non heat-sensitive group(three acupoints in no 1 a moxibustion sensation or a heat-sensitive moxibustion sensation of frequency of 1 day)or less.Two groups of subjects were all not changing the original drug,on the basis of heat-sensitive group in fengfu,dazhui ?yongquan(double side)for heat-sensitive moxibustion,points at the same time,moxibustion,45~50 min per acupuncture moxibustion,moxibustion 1 times a day,a month for a period of treatment,a total of intervention for 3 months(90d),2 days off between each course of treatment,acupuncture points,and the heat-sensitive group time and intervention treatment with heat-sensitive group.From the beginning ofthe study,the subjects were randomly selected and regularly interviewed.Telephone visits will be made once a week to understand the general situation,and home visits will be made once a month to measure blood pressure,monitor the subject's record of moxibustion,and investigate the moxibustion sensation and adverse reactions during moxibustion.The blood pressure of the subjects in the heat-sensitive group and the non-heat-sensitive group were measured before the intervention,during the follow-up at all stages and at the end of the intervention at the end of march,respectively.3 after the treatment,heat-sensitive group subjects based on the actual moxibustion frequency divided into low-moxibustion group(the average weekly number of moxibustion <3 times)and high-moxibustion group(moxibustion the number3 or more times a week on average),and the statistics of the two groups before intervention and intervention blood pressure value of the end of march,TCM symptom score,quality of life score duchenne hypertension,compare the curative effect of heat-sensitive group under different interference frequency difference.At the same time,adverse events were recorded in detail during the trial.Finally,all the data were summarized and statistical analysis was conducted using the software SPSS25.0.Results:1.Comparison of blood pressure values at different time points between the heat-sensitive group and the non-heatsensitive group: blood pressure values at different time points were compared between the two groups using repeated measurement anova.The overall comparison of systolic blood pressure and diastolic blood pressure was consistent with the sphericity test(P>0.05),the comparison of repeated measurement time points of the internal effects of subjects was consistent(P<0.05),the interaction effect test was consistent(P>0.05),and the comparison of intersubjective effects was consistent(P<0.05),which indicating thatthe overall comparison of systolic blood pressure and diastolic blood pressure was statistically significant.Comparison of systolic blood pressure and diastolic blood pressure between the two groups before intervention and between the end of February and the end of march before intervention showed statistical significance(P<0.05).Comparison of systolic blood pressure between the two groups at the end of February and the end of march before intervention showed statistical significance(P<0.05).Comparison of systolic blood pressure and diastolic blood pressure between the two groups showed statistically significant difference between the end of February and the end of march(P<0.05).2.Heat-sensitive group with the non-heatsensitive TCM symptom integral comparison: The points of heat-sensitive group before intervention was(69.40±10.69)and after intervention was(44.6±8.54)points.The points of non-heatsensitive group before intervention was(70.53±12.15),and after intervention was(52.94±13.76)points,The two groups respectively before and after the intervention group were statistically significant differences(P<0.01),the comparison between the two group intervention in late march,the difference was statistically significant(P<0.05);The difference of TCM symptom score between the two groups before and after intervention was statistically significant(P<0.05).3.The heat-sensitive group with the non-heatsensitive hypertension to compare quality of life scores:The points of the heat-sensitive group before intervention was(156.97±8.13)and after intervention was(189.92±9.77).The points of the non-heatsensitive group before intervention was(157.38±9.48)and after intervention was(180.76±10.70).The comparison between groups respectively before and after the intervention group wes statistically significant differences(P<0.01),the comparison between the two group intervention in late march,astatistically significant difference(P<0.01);The difference of duchenne's hypertension before and after intervention between the two groups was statistically significant(P<0.05).4.Comparison between the low moxibustion volume group and the high moxibustion volume group: The systolic blood pressure and diastolic blood pressure before intervention in the low moxibustion volume group were(165.58±14.49)mmHg and(100.54±7.83)mmHg,respectively.The systolic blood pressure and diastolic blood pressure of the high-moxibustion group were(167.56±13.92)mmHg and(101.82±7.74)mmHg respectively before and after the intervention,and(138.62±12.54)mmHg and(88.59±5.74)mmHg respectively at the end of march after the intervention.There were statistically significant differences between the two groups before and after the intervention(P<0.01).Systolic blood pressure and diastolic blood pressure at the end of march showed statistically significant difference between the two groups(P<0.05)and diastolic blood pressure(P<0.01).The point ofthe TCM symptom score was(69.46±11.25)before the intervention in the low moxibustion volume group,(47.92±10.24)at the end of march,The point of the TCM symptom score was(69.35±10.41)before the intervention in the high moxibustion volume group,and(42.06±5.98)at the end of march.By the end of march,the improvement of TCM symptoms in the high-moxibustion group was better than that in the low-moxibustion group,and the difference was statistically significant(P<0.05).The points of the Duchenne hypertension life quality score low moxibustion group was(157.38±8.80)before intervention,and(185.38±12.05)in late march.The point of the high quantity of moxibustion group was(156.65±7.70)before intervention and(193.38±5.66)in late march.the comparison between the two group respectively before and after the intervention group was statistically significant differences(P<0.01),the comparison between the two group intervention in late march,improvesthe quality of life of EH is superior to the high amount of moxibustion group low moxibustion group,the difference was statistically significant(P<0.05).5.Comparison of blood pressure efficacy: the total effective rate was83.33% in the heat-sensitive group and 61.76% in the non-heat-sensitive group,with statistically significant difference between the two groups(P<0.01).Compared with the high-moxibustion group,the total effective rate of the low-moxibustion group was 73.08%,and that of the high-moxibustion group was 91.18%.The difference between the two groups was statistically significant(P<0.05).6.Comparison of curative effect of TCM symptoms: The total effective rates of the thermal sensitive group and the non-thermal sensitive group were 90.00% and 73.53%,respectively,with statistically significant difference between the two groups(P<0.01).Compared with the high-moxibustion group,the total effective rate of the low-moxibustion group was 84.61%,and that of the high-moxibustion group was 94.12%,and the difference was statistically significant(P<0.05).7.Adverse events: No significant adverse events occurred during the test,and the safety level was level 2.Conclusion:1.Heat-sensitivemoxibustion intervention in community primary hypertension has a certain effect;2.Heat-sensitive moxibustion has a cumulative effect,adhere to the scientific regular moxibustion,the curative effect is significantly improved;3.Heat-sensitive moxibustion is safe and effective,non-toxic side effects,easy to operate,suitable for wide application in the community. |
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