Font Size: a A A

The Influence Of Gender, Age, Tumor Size And Location On The Benign And Malignant Tumors Of Meningioma Patients

Posted on:2020-11-16Degree:MasterType:Thesis
Country:ChinaCandidate:S W HuFull Text:PDF
GTID:2404330596983985Subject:Surgery
Abstract/Summary:PDF Full Text Request
Purpose:This study aims to make a single-center retrospective analysis of the factors affecting the nature of meningiomas.Through the collection an d classification of previous meningiomas,the gender,age,tumor location,tumor size and the benign and malignant characteristics of meningioma a re counted.Learn to analyze whether there is a correlation between relat ed variables.Methods:In this study,between June 2014 and June 2018,870 patients w ith intracranial space in our hospital were enrolled in the intracranial spa ce,and 870 patients with meningioma confirmed by pathology were used as analysis samples.Lack of hospital MRI,multiple meningioma,and spin al meningioma were excluded from the sample analysis and baseline data were recorded for the patients entering the group.The study classified the location of the tumor as the location of the convex surface of the brain,the base of the skull,and others.The largest diameter of the tumor is us ed as an indicator of tumor size.First,a differential analysis was perform ed on each group of variables.Second,single factor and multi-factor logis tic regression models were used to determine the relationship between vari ables and tumor properties.Finally,we measure the predictive value of re levant factors for the nature of meningioma.Results:A total of 870 cases of meningioma were collected,including 645 female patients,accounting for 74.1%,and 225 male patients,accounting f or 25.9%,with an average age of 55.3 years(11-85 years).There were 768 benign cases,accounting for 88.3%,and 102 cases(11.7%).The tumors were distributed as follows: 552 brain(63.4%),skull base,297(34.1%),a nd other sites in 21(2.5%).Difference analysis in each variable group sho wed that the average size of malignant meningioma was larger than that of benign meningioma(P<0.001);and age had no significant effect on the incidence of benign and malignant meningioma(P=0.99);gender was differ ent The composition ratio of benign and malignant meningiomas was diffe rent(P<0.001);the location of meningiomas was different,and the compos ition ratios of benign and malignant were different(P<0.001).Analysis of risk factors for benign and malignant meningioma showed that male(P<0.01),convex position of the brain(P<0.01)and tumor size(P<0.01)were in dependent risk factors for malignant meningioma,and had important pred ictive value.Conclusions:Male,patients with convex meningioma,and the larger the tumor,the more likely it is malignant meningioma.
Keywords/Search Tags:Benign meningioma, malignant meningioma, influencing factors
PDF Full Text Request
Related items