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Postoperative Pathological Analysis Of Upper Gastrointestinal Carcinoma And Precancerous Lesion

Posted on:2019-01-17Degree:MasterType:Thesis
Country:ChinaCandidate:C L JiFull Text:PDF
GTID:2404330602459194Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Part ?POSTOPERATIVE PATHOLOGICAL ANALYSIS OF ESOPHAGEAL CANCER AND PRECANCEROUS LESION IN GAS-TROSCOPY AND ESDObjectiveAnalysis of early esophageal cancer and precancerous lesions in patients with preoperative gastroscope biopsy pathologic results and ESD,consistent with the postoperative pathologic results and analysis of the influence factors of the result,looking for ways to improve the consistent rate,for the diagnosis of early esophageal cancer and precancerous lesions and provide clinical basis for treatment.MethodsSelection on January 1,2015-November 30,2017 in Qianfoshan hospital of shandong province above which conform to the inclusion criteria for 57 cases,statistical patients' age,gender,lesion size,lesion location,lesion form,the factors related to endoscopic doctor qualifications,endoscopic check for preoperative gastroscope biopsy pathologic results and ESD effect of consistent with the postoperative pathologic results.Results1.The effect of diameter of the lesion on the pathological consistency of ESD before and after surgery: P value was 0.017,less than 0.05,and the difference was statistically significant.2.The effect of endoscopic doctor's qualification on the pathological consistency of ESD before and after surgery:P value was 0.005,less than 0.05,which was statistically significant.3.Endoscopic lesions form impact on ESD preoperative postoperative pathological consistency: 0-?b coincidence rate is higher,P value is 0.000,less than 0.05,the difference was statistically significant.4.The effect of endoscopy(amplification and iodine dye)on the pathological consistency of ESD before and after surgery: P value was 0.000,< 0.05,and the difference was statistically significant.5.Most of the lesions were in the lower part of the esophagus,and the lesion site had no significant effect on the pathological consistency of ESD before and after surgery.6.The effect of gender and age on coincidence rate(P > 0.05)was not statistically significant.Conclusion1.The diameter of the lesion affected the pathologic consistency of ESD before and after surgery,and the smaller the lesion(maximum length < 2cm),the higher the postoperative biopsy pathology and postoperative ESD pathology.2.Endoscopic doctor's qualification has significant influence on the pathological consistency of ESD before and after surgery,and the higher the annual rate of endoscopic doctor,the higher the consistency between the pathological results of preoperative biopsy and the pathological results after ESD surgery.3.The lesion morphology of the endoscopic lesion showed an IIb type with higher coincidence rate before and after operation.4.Endoscopic examination(amplification and iodine dye)was compared with ordinary endoscopy,and the difference was statistically significant for the preoperative and postoperative concordant rate of ESD.5.Most of the lesions were in the lower part of the esophagus,and the lesion site had no significant effect on the pathological consistency of ESD before and after surgery.6.The gender and age of the patients had no statistically significant effect on the coincidence rate.Part ?COMPARATIVE ANALYSIS OF POSTOPERATIVE PATHOLOGY AND GASTROSCOPY IN EARLY GASTRIC CANCER AND PRECANCEROUS LESION AND ESD.ObjectiveAnalysis of early gastric cancer and precancerous lesions in patients with preoperative gastroscope biopsy pathology results consistent with ESD postoperative pathologic results,and analyzes the factors that influence the result of seeking to improve the consistent rate of solution,for early gastric cancer and precancerous lesions with endoscopic treatment basis.MethodsSelection on January 1,2015-November 30,2017 in Qianfoshan hospital of shandong province included in the standard of 103 cases,statistical patients' age,gender,lesion size,lesion location,lesion form,the factors related to endoscopic doctor qualifications,endoscopic check for preoperative gastroscope biopsy pathologic results and ESD effect of consistent with the postoperative pathologic results.Results1.The effect of the diameter of the lesion on the pathological consistency before and after ESD surgery: P value was 0.017,less than 0.05,and the difference was statistically significant.2.The effect of endoscopic doctor's qualification on the pathological consistency of ESD before and after surgery: P value was 0.001,less than 0.05,which had statistical significance.3.Endoscopic lesions form on postoperative pathological consistency: the influence of ESD preoperative endoscopic lesions form is 0-?a+?c type lesions coincidence rate is higher,P value is 0.046,P < 0.05,the difference was statistically significant.4.Endoscopy(magnification and indigo cochineal staining)was not significant in this study.5.The lesion site had an effect on the pathological consistency of ESD before and after surgery: most of the lesions were in the gastric antrum and the gastric body,and the consistency of the lesion site was compared,and the P value was greater than 0.05,and the difference was not statistically significant.6.The effect of gender and age on coincidence rate(P > 0.05)was not statistically significant.Conclusion1.The pathological and postoperative ESD pathology was higher in patients with lesion size < 2cm.2.Endoscopic lesion 0-?a+?c consistency was higher.3.The more advanced endoscopic doctors were,the higher the consistency of the pathological results of preoperative biopsy and ESD.4.The effect of endoscopic examination(amplification and vinegar dyeing-indigo carmine staining)on the pathological consistency of ESD before and after surgery: P value of 0.015,< 0.05 was considered statistically significant.5.Most of the lesions were in the gastric antrum and the gastric body,but had no significant effect on the pathological consistency of ESD before and after surgery.6.The effect of gender and age on the concordance rate was not statistically significant.
Keywords/Search Tags:Early esophageal cancer, precancerous lesion, biopsy, ESD, pathology, Early gastric cancer
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