Discussion On The Application Value Of Coagulation And Blood Lipid In Endometrial Carcinoma

Objective:To retrospectively analyze the difference of the blood coagulation function,D-dimer,platelet and blood lipid between patients with endometrial carcinoma and patients with endometrial benign lesions,and to explore the correlation and application value of these indicators with endometrial carcinoma.Methods:The clinical data of 92 patients with endometrial carcinoma and 92 patients with endometrial hyperplasia without atypia were retrospectively analyzed in our hospital from January 2015 to March 2019.Results:The plasma levels of fibrinogen,D-dimer,cholesterol and platelet in endometrial carcinoma patients were significantly higher than those in endometrial hyperplasia without atypia(P<0.05).Moreover the plasma levels of fibrinogen and D-dimer were increasing with the increase of the diferentiation and stage of endometrial carcinoma(P<0.05).However the plasma levels of the activated partial thrombopiastin time and the high density lipoprotein in endometrial carcinoma patients were significantly lower than those in endometrial hyperplasia without atypia(P<0.05).Conclusion:The high level of blood lipid can regards as the early-warning index in the endometrial carcinoma risk group.And the abnormal blood coagulation function can regards as the important index to evaluate the diferentiation and stage of endometrial carcinoma.And it can provide the basis to prevent occurrence,advancing and antithrombotic therapy of endometrial carcinoma.