Clinical Efficacy Of The Thrombosis Of Muscular Calf Vein In The Treatment Of Huomai Powder

Objective:To observe the clinical effect and advantages of Huomai Powder in the treatment of intermuscular venous plexus thrombosis in the lower leg,and to observe the anticoagulant effect of low dose rifaxaban tablet in the treatment of intermuscular venous plexus thrombosis in the lower leg,and to analyze whether there is statistical significance between the two.Methods:The patients were from October 2018 to December 2019 in the whole hospital of the affiliated hospital of Shanxi College of traditional Chinese Medicine.According to the random number table method,68 study samples were randomly divided into 34 cases in the treatment group and 32 cases in the control group.Treatment group:taking our own preparation Huomai Powder(Leech,Gadfly,Dilong,Panax notoginseng,Scorpion,etc.)8g,Control group:taking rivastaban tablets(Bayer Medical Health Co.,Ltd.,approval symbol H20140132),the first three weeks 10 mg,a day twice,maintenance dose of 15 mg,a day once.4 weeks,6 weeks,8 weeks,12 weeks after admission Check D dimer,Doppler ultrasound,compare the thrombus before and after the group and between the two groups.Result:1.This clinical observation included 66 effective cases,including 34 in the treatment group,0 in the shedding group,32 in the control group and 2 in the shedding group.2.general data(baseline comparison):there was no significant difference in sex and age between the two groups,and there was no statistical difference in TCM symptom score and western medicine laboratory index before treatment.;3.TCM syndrome score comparison:Prior to treatment,the treatment group and the control group compared,P>0.05,there was no statistical difference in statistical analysis,the two groups were comparable;after 4 weeks compared with before treatment,there was significant difference P<0.01 statistical analysis;after 6 weeks compared with 4 weeks of treatment,the difference was statistically significant.After 8 weeks compared with 6 weeks of treatment,P<0.01,there was a significant difference in statistical analysis;after 12 weeks compared with 8 weeks of treatment,P<0.05,the difference was statistically significant.4.The control group compared with the treatment group,after 4 weeks of treatment,the control group compared with the treatment group P<0.01,statistical analysis showed significant difference;after 6 weeks of treatment,the two groups compared P<0.05,the difference was statistically significant;after 8 weeks of treatment,the two groups compared PPP<0.05,the difference was statistically significant4.plasma D-dimer comparison results treatment group and control group,after 2 weeks,4 weeks,12 weeks of treatment compared with before treatment P>0.05.The plasma D dimer content in the treatment group and the control group increased 4 weeks after treatment compared with that before treatment,P>0.05,no statistical difference.the two groups after 8 weeks of treatment compared with before treatment,P<0.01,there was significant statistical difference;the plasma D dimer in the two groups after 6 weeks of treatment decreased compared with 4 weeks after treatment,P<0.05,there was a statistical difference.data showed that plasma D dimers showed first rise and then decrease change,reaching peak after 4 weeks of treatment.Compared with the two groups,the P values were greater than0.0 5.There was no difference in statistical analysis.Comparison of control group and treatment group,4 weeks after treatment,control group and treatment group compared P<0.01,statistical credits There were significant differences in analysis;after 6 weeks of treatment,the two groups compared P<0.05,the difference was statistically significant;after 8 weeks of treatment,the two groups compared P>0.05,the difference was not statistically significant;after 12 weeks of treatment,the two groups compared P<0.05,the difference was statistically significant.5.After 12 weeks of 5.treatment,the lower extremity color ultrasound Doppler revascularization was observed-vascularization:no thrombus recanalization in the treatment group 2 cases,partial recanalization in 17 cases,complete recanalization in 15 cases,no thrombus recanalization in the control group 3cases,partial recanalization in 19 cases,complete recanalization in 10 cases,χ~2 value was0.535,P>0.05 no significant difference in statistical analysis.Conclusion:Through the clinical observation of Huomai San and Lifashaban tablets in the treatment of intermuscular venous plexus thrombosis in the lower leg,the clinical observation shows that Huomai San is effective and has advantages in improving clinical symptoms and improving quality of life,and the effectiveness of insect-like Huoxue and removing stasis in the treatment of intermuscular venous plexus thrombosis in the lower leg is verified.The feasibility of small dose of rifaxaban tablets for the treatment of intermuscular venous plexus thrombosis in the lower leg was verified.This clinical observation provides a reference for the clinical treatment of the standardized treatment of intermuscular venous plexus thrombosis in the lower leg.