| Purpose:The clinical application value of BAEP in early identification and diagnosis of post-circulation cerebral infarction is explored preliminarily by analyzing characteristics of change in brainstem auditory evoked potentials(BAEP)in acute and chronic post-circulation cerebral infarction,and comparison of its relevancy with atherosclerosis.Method:In this study,patients with posterior-circulate infarction disease and receiving medical services in Department of Neurology in Shanghai Sixth People's Hospital from August,2018 to March 2419,are selected as subjects.According to cranial MRI,36 cases of acute posterior-circulation infarction patients are taken as Acute Group,32 cases of chronic infarction patients are taken as Chronic Group,meanwhile 32 healthy persons are selected as Control Group.The change characteristics of data,such as ?,?,and ? wave peak latency(PL),?-?,?-? and ?-? wave inter-peak latency(IPL),and?-?/?-? wave inter-peak ratio,are observed,and comparison and analysis of relevancy is performed together with medial thickness,plaque thickness,and stenosis ratio of carotid intimaResultThe BAEP results of 3 groups show 4.08±0.30mm and 6.09±0.4mm average ? wave and V wave peak latency,0.85±0.15mm average IMT of carotid artery,average 1.01 ± 1.15mm average plaque thickness,0.2±0.19 average stricture rate.The wave PL value has significant correlation(positive correlation)with,IMT the plaque thickness and the stricture rate with statistically significant difference(P<0.05).Vertebral artery ultrasonography indicates that,there are three cases whose unilateral vertebral artery blood flows slowly and one case whose unilateral vertebral artery resistance index increase in Acute Group,there are one case whose unilateral vertebral artery blood flows slowly in Chronic Group,and neither plaque nor obvious stenosis have been detected through examinationsFor Acute Group,average ? wave PL is 1.88±0.95ms,average ? wave PL is 4.39±0.25ms,average ? wave PL is 6.43±0.36ms,average ?-? wave IPL is 2.66±0.28ms,average ?-? wave IPL is 2.04±0.26ms and average ?-? IPL wave is 4.71 ±0.39ms.For Chronic Group,average ? wave PL is 1.73±0.13ms,average ? wave PL is 3.96±0.20ms,average ? wave PL is 6.04±0.26ms,average?-? wave IPL is 2.24±0.24ms,average ?-? wave IPL is 2.09±0.25ms,average ?-? wave IPL is 4.33±0.31ms.For Control Group,average ? wave PL is 1.666±0.11ms,average ? wave PL is 3.86±0.11ms,average ? wave PL is 5.74±0.16ms,average ?-? wave IPL is 2.19±0.13ms,average?-? wave IPL is 1.88±0.11ms and average ?-? wave IPL is 4.08±0.18ms.Acute Group with abnormal brainstem auditory evoked potential has extended ? and ? wave peak latency,and ?-?and ?-? wave inter-peak latency compared with those of Chronic Group,with statistically significant difference(P<0.05),?-? wave inter-peak latency which is not extended obviously compared with Chronic Group(P>0.05).Chronic Group has extended ? and ? wave peak latency and ?-? wave inter-peak latency compared with Control Group with statistically significant difference(P<0.05),and ?-? wave inter-peak latency without statistically significant difference(P>0.05)with Control GroupAcute Group includes one case involved with abnormal cochlea segment(2.8%),three cases involved with abnormal pons segment(8.3%),30 cases involved with abnormal cochlea segment and pons segment(83.3%),eight cases involved with abnormal single side(22.2%),26 cases involved with abnormal double side(72.2%).Chronic Group includes 0 case involved with abnormal cochlea segment(0%),1 one cases involved with abnormal pons segment(34.4%),6 cases involved with abnormal cochlea segment and pons segment(18.8%),12 cases involved with abnormal single side(37.5%),6 cases involved with abnormal double sides(18.8%).Total abnormal rate is 94.4%for Acute Group(34 cases)and 56.3%(18 case)for Chronic Group.The difference is statistically significant between two groups(P<0.05).Conclusion1.The electrophysiological anomaly of auditory sense pathway of patients,with acute and chronic post-circulation cerebral infarction disease,can be detected by BAEP examination,and it is positive correlated with degree of atherosclerosis.2.The BAEP examination of Acute Group indicates that,? and ? wave PL and ?-? and ?-? wave IPL are extended significantly,and extended ? wave PL and ?-? wave IPL are dommant;BAEP examination of Chronic Group indicates that,? and ? wave PL and ?-? and ?-? wave IPL are extended,and extended V wave PL and ?-? wave IPL are dominant.Characteristics of the brainstem dysfunction in acute and chronic post-circulation cerebral infarction are reflected objectively.3.Acute and chronic post-circulation cerebral infraction may cause functional lesion on cochlea segment or pons segment,and it can be differentiated from different characteristics shown through BAEP examination,to provide reliable functional index basis for early identification and prevention&treatment of posterior circulation brainstem dysfunction. |
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