Effect Of Low Body Weight On The Prognosis Of Patients After Heart Valve Replacement

Purpose:Body Mass Index(BMI),the weight value(kg)divided by the height(meter)square,is an important standard commonly used to measure the health of the human body.The normal BMI range for adults is 18.5-24.A large number of clinical studies have found that high BMI is closely related to many cardiovascular and metabolic diseases.However,there are few studies on the relationship between low BMI and cardiovascular disease.Heart valve disease is an important part of cardiovascular disease.The main treatment method is heart valve replacement.Therefore,the relationship between low body weight and heart valve replacement should be thoroughly studied.This clinic study aims to explore the impact of low body weight(BMI<18.5)on the prognosis of patients after heart valve replacement,and provide a theoretical basis for improving the treatment of patients with heart valve disease in clinical practice.Methods:A total of 223 patients undergoing heart valve replacement surgery in our department from January 2016 to January 2019 were studied.These patients were divided into two groups according to body mass index(BMI<18.5),those with low body weight(Group A,a total of 54 cases)and those with normal body weight(Group B,a total of 169 cases).Retrospective analysis was conducted to compare the postoperative complications and clinical prognosis of patients in each group,and the risk factors for death after cardiac valve replacement were analyzed by multivariate Logistic regression analysis.Results:With normal body weight(18.5≤BMI<24)group of patients,compared to small weight group(BMI<18.5)after surgery in a month on the day of death(including surgery)statistical differences in mortality(P=0.037),and operation method,details in the operation,postoperative pneumonia,breathing machine use time more than 24 hours after operation,postoperative incision infection has no significant statistical difference,Multivariate binary Logistic regression analysis showed that grade IV cardiac function,aortic occlusion time,High blood sugar,operation time,cardiopulmonary bypass time,cardiac ejection fraction,age,concurrent coronary artery bypass grafting,and small body weight were independent risk factors for death after cardiac valve replacement.Will the independent risk factors of death after heart valve replacement patients according to the OR sort of its intensity effect for postoperative death from high to low in turn for cardiac function level Ⅳ,age,heart ejection fraction,high blood sugar,small weight,operation time,at the same time of coronary artery bypass graft,extracorporeal circulation time,aortic block of timeConclusions:Small body weight can increase the mortality rate of patients after cardiac valve replacement,but has no significant effect on postoperative pulmonary infection,postoperative recurrent atrial fibrillation,postoperative ventilator use time over 24 hours,postoperative cardiac arrest or ventricular fibrillation,etc.Small body weight is an independent risk factor for death after cardiac valve replacement.