A Study On The Correlation Between 30-second Sit-to-stand Test And Exercise Endurance Of Patients With Chronic Obstructive Pulmonary Disease

Objective:To evaluate the correlation between the number of sit-to-stand within 30 seconds and exercise endurance in stable patients with chronic obstructive pulmonary disease,and to discuss whether the sit-to-stand test can be used as the initial screening method for decreased exercise endurance of patients with COPD.Methods: Totally 98 patients with stable COPD were recruited,they completed 6minutes walk test and two 30-second sit-to-stand tests,and researchers measure the patients' quadriceps muscle strength,pulmonary function,height,weight,body mass index,etc.We use Spearman correlation coefficient to analyse the correlation between each variable and establish a ROC curve to evaluate the predictive ability of30-second sit-to-stand test for 6 minutes walking distance < 350 m.Results: There was a good retest reliability(ICC=0.975,95%CI:0.962?0.983)in the two 30-second sit-to-stand tests.The number of sit-to-stand in 30 seconds was significantly positively correlated with the 6 minutes walking distance,quadriceps muscle strength,FEV1% pred,FVC,FEV1/FVC(P<0.05),and the correlation coefficients were 0.466?0.315?0.319?0.262?0.264.The ROC curve showed that the number of sit-to-stand in 30 seconds was <24,indicating that the patient had a risk of decreased exercise endurance(6 minutes walking distance <350 m).Bivariate logistic regression analysis showed that the 30-second sit-to-stand test was the determinant of exercise intoleranc(OR=1.136,95%CI=1.022?1.223,P=0.018).Conclusion: The number of sit-to-stand test in 30 s and 6-minute walking distance are significant correlated,so 30-second sit-to-stand test can be used as a preliminary screening tool to evaluate exercise endurance of patients with COPD.