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Correlation Analysis Of Prostate Small Extravasation Protein With NIH-CPSI Score And EPS Detection Indicators

Posted on:2021-01-16Degree:MasterType:Thesis
Country:ChinaCandidate:Z QiFull Text:PDF
GTID:2404330614463532Subject:Surgery
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Chronic prostatitis is one of the most common diseases in urology clinics,accounting for about 30%of outpatients,and often occurs in young and middle-aged patients.Its etiology,pathogenesis and diagnostic methods are very complex,and so far there is widespread controversy.In recent years,research found that prostate epithelial cells can secrete a genital membranous vesicle,which contains protein components and can enter the prostate fluid and urine,known as prostate small extravasation protein.In related research,when the prostate is inflamed,the content of prostate small extravasation protein in the urine will increase,indicating that it can be used as an indicator for the detection of chronic prostatitis.In order to further study the value of prostate small extravasation protein in the diagnosis of chronic prostatitis,we propose a correlation analysis between the prostate small extravasation protein and the NIH-CPSI score and EPS detection indicators.Objective:To explore the correlation between prostate small extrava-sation protein and NIH-CPSI score and EPS detection indicators.Methods:The research includes a screening phase,a processing phase,and a statistics phase.In the screening phase,we selected 74 patients with chronic prostatitis from the outpatient clinic of the Second Hospital of Hebei Medical University,and conducted medical history inquiry,physical examination and laboratory evaluation.Treatment phase:All patients completed the NIH-CPSI scale and measured the prostate small extravasation protein in the urine as well as the conventional indicators(WBC and SPL counts)in EPS.Statistical stage:Statistical analysis was performed using SPSS23.0 statistical software:Statistical analysis of the correlation between the prostate small extravasation protein in patients with chronic prostatitis and its NIH-CPSI score and EPS detection indexResults:Patients with chronic prostatitis have a significant correlation between the prostate small extravasation protein in the urine and its NIH-CPSI score(r_s=0.530,P=0.000),and a significant correlation with the WBC count in EPS(r_s=0.649,P=0.000),there is no significant correlation with the SPL count in EPS(r_s=-0.103,P=0.385).Conclusion:The prostate small extravasation protein can reflect the severity of chronic prostatitis,and can be used as an important indicator for the diagnosis of chronic prostatitis.
Keywords/Search Tags:Chronic prostatitis, Prostate small extravasation protein, National Institutes of Health chronic prostatitis symptom index, Expressed prostatic secretio, Small particle of lecithin, White blood cell
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