Analysis Of Risk Factors For Patients With Colorectal Polyps

Objective:This article aims to investigate the impact of various factors on the incidence of colorectal polyps by investigating the basic personal information,lifestyle habits,family history,and history of underlying diseases,etc.,of colorectal polyps patients.And screen out high-risk group by analyzing the risk factors and independent risk factors of colorectal polyps patients.Thus provide valuable reference materials for effective prevention and treatment of colorectal polyps.Methods:Patients performed with electronic colonoscopy at Beijing Jiangong Hospital from January 2018 to August 2019 were selected as research subjects.Their clinical data were systematically reviewed and analyzed.According to the inclusion and exclusion criteria after strict selection,500 colorectal polyps patients were selected as the case group,and another 500 showed no cases of abnormality with electronic colonoscopy were selected as the control group.Personal data was collected through the electronic medical record system and medical records.Including patients’ basic personal information and lifestyle habits(name,gender,age,height,weight,smoking history,drinking history),family history of tumor,past medical history(hyperlipidemia,hypertension,type 2 diabetes,coronary heart disease,cerebral infarction,history of cholecystectomy,non-alcoholic fatty liver disease NAFLD)etc.As well as the electronic colonoscopy report and pathology report of selected patients.All the collected data were sorted,entered into an Excel table,and after verification,used the statistical software SPSS21.0 for statistical analysis.Results:1.Correlation between colorectal polyps and various risk factors(1)Risk factors such as age,gender,smoking history,drinking history,family history of tumor,hyperlipidemia,hypertension,and NAFLD in the case group were statistically significant(P <0.05),while factors such as history of cholecystectomy,type 2 diabetes,coronary heart disease,cerebral infarction in the case group were with no statistical difference(P> 0.05).(2)Among the case group,there were 118 single polyps and 382 multiple polyps.Among the multiple polyps group,the proportions of patients who were male,with an older age,smoking history,family history of tumor,hyperlipidemia,and type 2 diabetes were higher than those with single polyps(P <0.05).There was no statistical difference in other indicators(P> 0.05).(3)There were 237 cases of advanced adenoma and 263 cases of polyps of non-progressive adenoma.Which showed statistical differences in factors such as male,age,smoking history,family history of tumor,type 2 diabetes,hyperlipidemia(P <0.05),while no statistical difference in other indicators(P> 0.05).(4)Multivariate logistic regression analysis showed that older male,people with a family history of tumor or hyperlipidemia,were at higher risk of colorectal polyps.2.Correlation between colorectal polyps and various risk factors in youth group(1)There were no statistically significant differences in age,gender,smoking history,drinking history,family history of tumor,history of cholecystectomy,hyperlipidemia,hypertension,type 2 diabetes,coronary heart disease,cerebral infarction,and NAFLD(P> 0.05).(2)In the case group,there were 14 cases of single polyps and 5 cases of multiple polyps,and there was no statistically significant difference in each indicator(P> 0.05).(3)The proportions of patients with hyperlipidemia,hypertension,and type 2 diabetes in the advanced adenoma group of the case group were higher than those of the non-progressive adenoma polyps group,and there were statistical differences(P <0.05),and the other indicators were with no statistically difference(P> 0.05).(4)Multivariate unconditional logistic regression analysis showed that young people with NAFLD had a higher risk of colorectal polyps.3.Correlation between colorectal polyps and various risk factors in middle-aged group(1)Risk factors such as age,gender,smoking history,drinking history,family history of tumor,and hyperlipidemia in the case group were statistically significant(P <0.05).However factors such as cholecystectomy history,hypertension,type 2 diabetes,coronary heart disease,cerebral infarction,NAFLD were with no statistical difference(P> 0.05).(2)The proportions of patients who were male,with an older age and smoking history in the multiple polyps group of the case group were higher than those of single polyps,thus there were statistical differences(P <0.05).The other indicators were with no statistically difference(P> 0.05).(3)In the case group,the proportions of patients who were male,aged 55-59 years old,with smoking history,family history of tumor,hyperlipidemia,and coronary heart diseasein the advanced adenoma group were higher than those in the non-progressive adenoma polyps group,thus there were statistical differences(P <0.05).There was no statistical difference in other indicators(P> 0.05).(4)Using Multi-factor unconditional logistic regression analysis,as well as the stepwise backward regression method,the results showed that people with higher ages among middle-aged men and with a family history of tumoror hyperlipidemia,had a higher risk of colorectal polyps.4.Correlation between colorectal polyps and various risk factors in the elderly group(1)Risk factors such as age,gender,smoking history,drinking history,family history of tumor,hyperlipidemia,and NAFLD in the case group were statistically significant(P <0.05),history of cholecystectomy,hypertension,type 2 diabetes,coronary heart disease,cerebral infarction in the case group were with no statistical difference(P> 0.05).(2)The proportions of patients with a smoking history,family history of tumor,hyperlipidemia,and type 2 diabetes in the multiple polyps group of the case group were higher than those of the single polyps group,with statistically significant differences(P <0.05).And the remaining indicators were not statistically different(P> 0.05).(3)The proportions of patients who were male,aged between 60-65 years old,with smoking history,family history of tumor,hypertension in advanced adenoma group were higher than those in non-progressive adenoma polyps group(P <0.05),other indicators were not statistically different(P> 0.05).(4)Multivariate unconditional logistic regression analysis showed that older men,with a family history of cancer or hyperlipidemia,hypertension,and NAFLD had a higher risk of colorectal polyps.Conclusions:1.Male,with an older age,smoking,drinking,with family history of tumor,hyperlipidemia,hypertension and non-alcoholic liver disease are risk factors of the incidence of colorectal polyps.2.Senior people or male,along with a family history of smoking or tumors or hyperlipidemia are at higher risk of multiple polyps and advanced adenomas.