Preliminary Study On The Practicality Of RFH-NPT In Nutritional Risk Screening For Patients With Liver Cirrhosis

Objective: To explore the feasibility of Royal Free Nutrition Evaluation Priority Tool(RFH-NPT)for the screening of nutritional risk in patients with liver cirrhosis in China,to understand the incidence of nutritional risk in patients with liver cirrhosis,and to analyze the relational factors affecting the occurrence of nutritional risk.Methods: We collected 81 patients diagnosed as liver cirrhosis who came from our hospital from June 2019 to December 2019.These patients whose age rang from 18-79 years included 49 males and 32 females.According to the etiology,53 cases of hepatitis B,3 cases of hepatitis C,3 cases of alcoholic liver disease,2 cases of autoimmune liver disease,5 cases of primary biliary cholangitis,1 case of Wilson disease,14 cases of unexplained liver cirrhosis were included in this study.We collected basic information,diagnosis of the disease,clinical outcomes,serological indicators,RFH-NPT scores of these patients to establish an information collection form.We divided them into nutrition risk group and non-nutrition risk group based on the RFH-NPT nutrition risk screening scores.We analyzed the correlation between nutritional risk screened by RFH-NPT and clinical outcomes.We compared the etiology,gender,age,serological index,and Child-Pugh classification of liver function in the nutritional risk group with the non-nutrition risk group in the same period to find the factors that affect the nutritional risk of patients with liver cirrhosis.SPSS software was used for statistical analysis.Results:1.We collected 81 patients with cirrhosis.There were 48 patients in nutritional risk group screened by RFH-NPT and 33 non-nutritional risk group.The incidence of nutritional risk was 59.26%;2.The incidence of infection and hepatic encephalopathy was 35.42% and 22.92% respectively in nutritional risk group screened by RFH-NPT which was 9.09%、6.06% respectively in non-nutrition risk group.There were statistical differences between the two groups.The P value was 0.007 and 0.042 respectively;The length of hospitalization in the nutritional risk group was 11.50(7.80)days,which was 9.00(4.00)days in non-nutritional risk group.There was statistical significance between the two groups(P= 0.048);3.Single factor analysis showed the incidence of nutritional risk was related to old age,degree of complications,liver function Child-Pugh classification,albumin level and prothrombin time.P value is less than 0.05.Conclusion:1.RFH-NPT is a suitable nutritional risk screening tool for patients with cirrhosis in China,which can help clinical doctor identify the nutritional risk of patients with cirrhosis.It is easy to apply and promote;2.The incidence of nutritional risk in patients with cirrhosis screened by RFH-NPT is high;3.The factors which affect nutritional risk screened by RFH-NPT include age 60 years or older,degree of complications,liver function Child-Pugh classification,albumin level and prothrombin time.We should pay attention to these factors in nutritional risk screening for patitents with cirrhosis.