Effects Of Non-ablative 1540nm Fractional Laser And β Ray Irradiation For Pathological Scar Treatment

Background and Objective:Pathological scars included hypertrophic scars and keloids.They were caused by cutaneous injury and irritation.Continuous and histologically localized inflammation increased the number of fibroblasts in the reticular layer.Various modalities had been used to treat pathological scars.Radiotherapy was a good way to prevent recurrence in scars,but pigment changes always occurred after treatment.And fractional laser had the advantages in improving appearance.This study was to observe the effects of non-ablative 1540 nm fractional laser andβray irradiation in the treatment of pathological scars.Methods:Thirty-eight pathological scars from thirteen patients were enrolled.Three to five treatments of non-ablative 1540 nm fractional laser were conducted for each scar lesion which had about 1 month interval.Then,⁹⁰Sr radiation therapy was applied from the following days for one to four times.All patients were followed-up for over 6 months.The pictures of the scars before and after the treatment were taken.The VSS score,effective rate,satisfaction degree and adverse reaction were recorded.Results:30 patients completed the whole treatment.Each of the pathological scars received laser therapy three to five times and radiotherapy three to twelve times.After the last treatment total effective rate was 89.5%.We evaluated the total effective rate using VSS.The rate is 94.7%.The satisfaction of patients was 96.7%.Some patients showed edema,erythema and mild pain.The symptom decreased with ice compress.No severe adverse effect was observed.During the six months follow-up,no scar relapse was observed.Conclusion:The combination of non-ablative 1540 nm fractional laser andβray irradiation was noninvasive,effective and safe for pathological scars.It is worthy of clinical application and further research.