Correlation Between Carotid Atherosclerotic Plaque And Neurological Impairment And Short-term Prognosis In Patients With Cerebral Infarction

Objective: This study analyzed the clinical data of patients with acute cerebral infarction and explored the relationship between carotid plaque and cerebral infarction,and provided theoretical basis for the prevention,treatment and prognosis evaluation of cerebral infarction.Methods: A total of 99 patients with acute anterior circulation cerebral infarction who were admitted to the Department of Neurology,Affiliated Central Hospital of Shenyang Medical College from June 20 to 2019 were enrolled in the cerebral infarction group.The onset time was less than 24 hours.Acute anterior circulation cerebral infarction was diagnosed by CT scan and MRI.Patients who met the diagnostic criteria for acute cerebral infarction and informed consent were enrolled in the general data questionnaire.The NIHSS scores were performed at the time of admission.The m RS and BI scores were scored after 2 weeks of treatment,and were analyzed according to the data.Carotid plaque was compared between the cerebral infarction group and the control group.To analyze the relationship between NIHSS scores and carotid plaque in patients with cerebral infarction.To analyze the relationship between m RS score and BI score and carotid plaque in patients with cerebral infarction.Results:(1)Compared with the control group,the carotid intima-media thickness and number of plaques in the cerebral infarction group were significantly higher than those in the control group(P<0.01).The unstable plaques in the cerebral infarction group accounted for more,while the stable plaques in the control group accounted for more,the difference was statistically significant(P<0.05).In the plaque site,there was no statistical difference between the cerebral infarction group and the control group(P>0.05).(2)CIMT,carotid plaque number,and plaque stability were positively correlated with NIHSS scores in patients with cerebral infarction.(3)CIMT and plaque type were positively correlated with m RS score and negatively correlated with BI score.Conclusions:(1)The occurrence of cerebral infarction is closely related to carotid plaque;(2)The more severe the degree of carotid plaque,the more severe the neurological function and coma of NIHSS in cerebral infarction.(3)The more severe the degree of carotid plaque,the worse the prognosis of cerebral infarction.