| Objective: The combined use of lineal polypeptide and tegafur was analyzed to evaluate its effect on the immune function of patients with advanced colorectal cancer.Methods: This study selected 40 patients diagnosed with intermediate and advanced colorectal cancer who need to be treated with chemical drugs at the General Center of Ningxia Hui Autonomous Region People’s Hospital from December 2018 to December 2019,and comprehensively evaluate the patients’ related diseases Situation,to exclude the contraindications of related chemical drug treatment,combined use of lineal polypeptide and tegafur in the process of chemical drugs treatment,and to obtain data on immunoglobulin,lymphocyte subsets and related adverse reactions during chemotherapy,Use SPSS 19.0 statistical software for statistical analysis and obtain relevant data.Results:The data of leucopenia,thrombocytopenia,nausea,vomiting,fever,diarrhea and other adverse reactions before and after treatment with chemical drugs were not significant;the concentrations of immunoglobulins G,A,and M before chemotherapy were9.98±1.57g/L,2.29±0.49g/L,and 0.39±0.10g/L,after treatment with chemical drugs,it was13.37±1.91g/L,3.16±0.62g/L,0.61±0.15g/L.Comparing the immunoglobulin concentrations of the two groups,it is suggested that there is a statistical difference The significance of the study indicates that the lineal polypeptide can increase the immunoglobulin concentration before and after chemotherapy;the percentages of T,B lymphocytes and NK cells before chemotherapy are 41.13±4.84%,10.59±1.75%,21.53±3.10%,chemical drug treatment In the latter group,they were 48.52±7.08%,13.95±2.06%,and 26.42±3.72%.Comparing the percentage of lymphocyte subgroups in the two groups showed that the difference between the two groups was statistically significant,indicating that the lineal polypeptide could improve chemical treatment.The percentage of lymphocyte subsets before and after treatment.Conclusion: Lineal polypeptide can effectively improve the immune function of patients with mid-advanced colorectal cancer undergoing Teggio chemotherapy... |
