Study On Common Pathogenic Microorganisms Of Cervicitis

Objective:To study the common pathogenic microorganisms of cervicitis under the condition of vaginal micro-ecological balance and bacterial vaginosis,and provide reference for effective diagnosis and treatment of cervicitis.Methods:Patients with cervicitis who were admitted to the gynaecological clinic of Shanxi Bethune Hospital from January 2018 to January 2019 were randomly selected.Forty-eight patients with simple cervicitis under the basic balance of vaginal micro-ecology were used as group A,and 23 patients with bacterial vaginosis and cervicitis in the same period were treated as group B.Gram-stained smear examination of vaginal secretions in patients with A and B,aerobic bacteria culture outside the cervix,and mycoplasma culture in the cervical canal,and 8 cases of patients with purulent cervical secretions were added.Neisseria gonorrhoeae nucleic acid detection.The results of aerobic and mycoplasma test in patients with A and B were compared.The results of pathogenic microorganisms in 8 patients with purulent secretions were analyzed to understand the common pathogenic microorganisms of cervicitis in two different vaginal micro-ecological environments.Results:1.The detection rate of aerobic bacteria in group A was 14.583%(7/48),and the detection rate of aerobic bacteria in group B was 21.739%(5/23).The results of aerobic bacteria culture in group A and group B were compared.The difference was notsignificant(χ2=1.647,P=0.200).2.The detection rate of mixed infection of Ureaplasma urealyticum and Mycoplasma hominis in group A was 25.000%(12/48),and the detection rate of mixed infection of Ureaplasma urealyticum and Mycoplasma hominis in group B was 21.739%(5/23).There was no significant difference in the results of mixed infection of Ureaplasma urealyticum and Mycoplasma hominis in group A and group B(χ2=0.091,P=0.763).3.The detection rate of Ureaplasma urealyticum in group A was68.750%(33/48),and the detection rate of Ureaplasma urealyticum in group B was60.870%(14/23).The results of culture of Ureaplasma urealyticum in group A and group B were statistically collected.The difference was not significant(χ2=0.432,P=0.511).4.The detection rate of human mycoplasma in group A was 27.083%(13/48),and the detection rate of human mycoplasma in group B was 26.087%(6/23).There was no significant difference in the results of culture of Mycoplasma hominis in group A and group B(χ2=0.008,P=0.929).5.Eight patients with cervical secretions were purulent.The results of N.gonorrhoeae nucleic acid test were all negative.Aerobic bacteria culture detected Enterococcus faecalis,Escherichia coli and Streptococcus angina;Mycoplasma culture was detected.Human mycoplasma or(and)Ureaplasma urealyticum.Conclusion:1.Aerobic bacteria may be involved in the development of cervicitis in women of childbearing age,but may not be the main cause of the disease;2.Ureaplasma urealyticum may be a potential cause of cervicitis;3.Human mycoplasma may be a causative factor of cervicitis;4.The association between Neisseria gonorrhoeae and cervicitis may be related to ethnic,regional and cultural differences.