The Predictive Value Of Preoperative Urinary Microalbumin To Creatinine Ratio Level In Early Diagnosis Of Contrast-induced Nephropathy

Objective.To investigate the predictive value of preoperative urinary microalbumin to creatinine ratio(UACR)level for early diagnosis of contrast-induced nephropathy(CIN).Methods.A total of 180 patients scheduled to undergo elective coronary angiography(CAG)/percutaneous coronary intervention(PCI)in our department from November 2016 to September 2017 were selected into this prospective study.Patients were allocated to high UACR group(UACR?30,n=35)and control group(UACR<30,n=145)according to the UACR level.The patients were also divided into CIN group(n=32)and no CIN group(n=148).Multivariable logistic regression model was used to investigate the risk factors of CIN.Results.32 patients developed CIN(17.78%).The incidence of CIN was significantly higher in high UACR group than in the control group(P<0.001).The ratio of high UACR in CIN group was significantly higher than no CIN group(P<0.001).Multivariable logistic regression analysis indicated that preoperative UACR level(P<0.001,95%CI: 3.819~29.223,OR: 10.564)was an independent risk factor and a predictive factor of CIN.Conclusion.Preoperative UACR level appears to be an independent predictive factor for early diagnosis of CIN.