| Objective:By observing the therapeutic effect of manipulation combined with traditional Chinese medicine on the anxiety state of patients with perimenopausal cervical spondylotic vertebral arteriopathy(kidney asthenia and liver depression),the pathological mechanism of comorbidity between cervical spondylotic vertebral arteriopathy and anxiety state was further studied,and the mechanism of neck and shoulder facial manipulation and the method of "soothing liver tonifying kidney" was further discussed.Methods:The 60 female patients who met the diagnostic criteria and inclusion criteria were randomly divided into the control group and the treatment group using the random number table method,with 30 cases in each of the two groups.The basic data of age,medical history,symptoms and signs of the two groups were collection and statistics before enrollment.The Vp,Vm,PI and RI of vertebral basalar artery were examined by TCD,and the indexes such as FS-CSA,HAMA and PSQI were evaluated.In the treatment group,oral administration of chinese medicine decoction and neck shoulder facial manipulation treatment were given under the principle of "soothing liver tonifying kidney".In the control group,western medicine and traction of occipital and jaw band were given.The two groups were treated for 14 days.Finally,a database of relevant data before and after treatment was established,and SPSS21.0 statistical software was used for statistical analysis and description of the data.Results:1.HAMA improvement rate after treatment was compared between the two groupsIn the treatment group,5 cases were cured,18 cases had obvious effect,5 cases had improvement,and 2 cases were ineffective.In the control group,1 case was cured,8 cases had obvious effect,13 cases had improvement,and 8 cases were ineffective.The above results were statistically tested with P<0.05,indicating statistically significant difference in HAMA improvement rate between the two groups after treatment.2.HAMA scores at different time points before and after treatment were compared between the two groupsThe interaction between the two groups at different time points,between the groups and between the time and the grouping was statistically significant(P<0.05).At the same time point,there were no statistically significant differences between the two groups before the intervention(P>0.05).After treatment,the differences between groups at different time points were statistically significant(P<0.05).Compared with the same group at different time points,In the control group,the differences at different time points before and after treatment were statistically significant(P<0.05).There was no significant difference between after treatment and 7 days after treatment(P>0.05).The difference was statistically significant after treatment and 14 days after treatment(P<0.05).The difference between 7 days after treatment and 14days after treatment was statistically significant(P<0.05).In the treatment group,the differences at different time points before and after treatment were statistically significant(P<0.05).The difference was statistically significant after treatment,7 days after treatment and14 days after treatment(P<0.05).There was no significant difference between 7 days after treatment and 14 days after treatment(P>0.05).3.PSQI scores at different time points before and after treatment were compared between the two groupsThe interaction between the two groups at different time points,between the groups and between the time and the grouping was statistically significant(P<0.05).At the same time point,there were no statistically significant differences between the two groups before the intervention(P>0.05),bu the differences at different time points after treatment were statistically significant.Compared with the same group at different time points,The pairwise comparison between the two groups at different time points before and after treatment was statistically significant(P<0.05).Pairwise comparison at different time points after treatment had no statistical significance.4.FS-CSA scores at different time points before and after treatment were compared between the two groupsThe interaction between the two groups at different time points,between the groups and between the time and the grouping was statistically significant(P<0.05).At the same time point,there were no statistically significant differences between the two groups before the intervention(P>0.05),bu the differences at different time points after treatment were statistically significant.Compared with the same group at different time points,The pairwise comparison between the two groups at different time points before and after treatment was statistically significant(P<0.05).The pairwise comparison of the control group at different time points after treatment was statistically significant(P<0.05).However,pairwise comparison of the treatment group at different time points after treatment had no statistical significance(P>0.05).5.Comparison of various TCD examinations of basilar artery before and after treatment between the two groupsThe comparison of Vp value:The difference between the two groups before treatment was not statistically significant(P>0.05),and the difference between the two groups after treatment was statistically significant(P<0.05).Before and after treatment in the same group,the difference before and after treatment in the control group was not statistically significant(P>0.05),while the difference before and after treatment in the treatment group was statistically significant(P<0.05).The comparison of Vm value:The difference between the two groups before treatment was not statistically significant(P>0.05),and the difference between the two groups after treatment was statistically significant(P<0.05).Before and after treatment in the same group,the difference before and after treatment in the control group was not statistically significant(P>0.05),while the difference before and after treatment in the treatment group was statistically significant(P<0.05).The comparison of PI value:There was no significant difference between the two groups before and after treatment(P>0.05).The differences between the two groups before and after treatment were statistically significant(P<0.05).The comparison of RI value:There was no significant difference between the two groups before and after treatment(P>0.05).The differences between the two groups before and after treatment were statistically significant(P<0.05).Conclusion:The combination of manipulatione and traditional Chinese medicine in the treatment of peri-menopausal patients with anxiety state of Cervical spondylotic vertebral arteriopathy is effective.Compared with the control group,in HAMA,PSQI,FS-CSA in three aspects,the treatment can better improve the CSA patients anxiety caused by the anxiety,sleep disorder and psychological,dysfunction,and can significantly improve basal artery Vp and Vm index. |
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