Clinical Observation Of Antitussive Prescription In The Treatment Of Pertussis Syndrome(Phlegm Hot Glue Resistance Syndrome)

ObjectiveThe purpose of this study was to observe the clinical efficacy and safety of antitussive prescription in the treatment of pertussis syndrome(phlegm heat glue resistance syndrome),It also discusses the legislative basis and the thought of antitussive prescription,so as to provide a new treatment idea for traditional Chinese medicine in the treatment of pertussis syndrome.Selection methodsFrom January 2019 to January 2020,60 children with pertussis syndrome in the pediatric outpatient department of the first affiliated hospital of anhui university of traditional Chinese medicine were selected.According to the random number grouping method,they were divided into control group and experimental group,with 30 cases in each group.On the basis of conventional symptomatic support therapy,the control group was given western medicine(oral administration of azithromycin),and the experimental group was given oral administration of cough suppressant prescription compound granules on the basis of the control group.The observation course was 2 weeks.The changes of syndrome score and lymphocyte percentage in peripheral blood before and 2 weeks after treatment were statistically analyzed.After the end of treatment,the patients were followed up for 2 weeks to compare the recurrence rate of the two groups and analyze the long-term efficacy of the two groups’ treatment regimens.Results(1)In terms of curative effect,the total effective rate of the experimental group was 96.67%,and that of the control group was 76.67%.After chi-square test,P=0.045(P<0.05),the difference was statistically significant,and the curative effect of the experimental group was better than that of the control group.(2)In terms of reducing the score of the children’s main syndrome score,after t test,showed that P<0.05,and the difference was statistically significant,the experimental group was superior to the control group.In terms of reducing the totalsyndrome score,the t test showed that P<0.05,and the difference was statistically significant,the experimental group was superior to the control group.(3)In terms of improving vomiting,asthma and pulse condition(fingerprint),after chi-square test showed that P<0.05,and the difference was statistically significant.The curative effect of the experimental group was better than that of the control group.In terms of the improvement of other symptoms and signs such as the number of spasticity,duration of spasticity,shortness of breath,lingual frenulum ulcer,after chi-square test showed that P>0.05,was not statistically significant,and there was no significant difference between the experimental group and the control group.(4)In terms of analyzing the change of peripheral blood lymphocyte percentage,after t test showed that:P<0.05,the difference was statistically significant.Both treatment regiments could reduce the peripheral blood lymphocyte percentage value.Comparison between groups:P>0.05,no statistically significant difference;The two groups were equally effective in reducing the percentage of lymphocytes in peripheral blood.(5)According to the chi-square test,P>0.05,was not statistically significant,suggesting that the efficacy of the two groups had nothing to do with the age,course and condition of the children.ConclusionFor pertussis syndrome(Phlegm and hot gel resistance syndrome),the method of purging lung heat,purging phlegm and relieving cough can significantly improve the cough symptoms of children,and the curative effect is significant.This experiment has confirmed the clinical efficacy of the anti cough prescription in the treatment of pertussis syndrome(phlegm hot glue resistance syndrome),with no obvious toxic and side effects,drugs and doses are safe and reliable,which is worthy of promotion in clinical practice.For the treatment of pertussis syndrome to provide a more safe and effective treatment methods and ideas.