| Objective: To investigate the safety,feasibility,minimally invasive and clinical effects of laparoscopic radical resection of colorectal cancer in patients over 75 years old.Methods:,A total of 130 patients with colorectal cancer radical resection who were over 75 years old in general surgery department of Guangzhou Red Cross Hospital were collected,from 2014 to 2017.According to the surgical methods,90 cases were divided into laparoscopic surgery group(LAP group)and 40 cases were divided into open surgery group(OP group).The basic clinical data,operation conditions,operation specimen information,whether to enter ICU after operation,postoperative complications,hospitalization time,hospitalization expenses and follow-up of survival conditions of patients in the two groups were counted.The outcomes were analyzed with SPSS statistical software.Results: In this study,there were no statistically significant differences in the basic clinical data(gender,age,history of abdominal surgery,tumor location,ASA grade,and basic diseases)between the two groups(P>0.05),which was comparable.The average operation time of LAP group(208.82 ± 39.57min)was significantly different from that of OP group(183.82 ± 33.97min)(P<0.05).The incision length of LAP group(5.91 ± 0.51cm)was statistically different from that of the OP group(18.10 ±3.37cm).The average intraoperative bleeding volume of LAP group(68.11 ±57.39ml)was statistically different from that of OP group(110.75±48.33ml)(P<0.05).There was a significant difference between LAP group(3.02±0.82d)and OP group(4.40±1.77d)in postoperative first exhaust time(P<0.05).Meanwhile,there was a significant difference between LAP group(5.30±1.31d)and OP group(6.40±2.93d)the time of first postoperative fluid inflow(P<0.05).There was no significant difference between LAP group(7.53±2.28d)and OP group(8.35±4.70d)with postoperative abdominal drainage time(P>0.05).There was no significant difference in operation specimens between the two groups(P>0.05).There was no statistically significant difference between the two groups in whether patients were admitted to the ICU for postoperative treatment(P>0.05),but there was a statistically significant difference between patients aged 75?84 years and patients more than 84years(P<0.05).There were 25 cases(27.7%)of postoperative complications in the LAP group and 17 cases(42.5%)in the OP group,with no significant difference between the two groups(P>0.05).The hospitalization time in LAP group(15.84±7.27d)was significantly different from that in OP group(20.40±10.28d)(P<0.05).There was no significant difference in hospitalization cost and 2-year survival rate between the two groups(P>0.05)Conclusion: In elderly patients with colorectal cancer(375 years old),compared with open surgery,laparoscopic radical resection of colorectal cancer has similar clinical effect in postoperative complications,operation specimen information and 2-year survival rate,which was safe;Laparoscopy is superior to traditional open surgery in terms of intraoperative bleeding volume,incision size,postoperative gastrointestinal function recovery and hospitalization time,which is more minimally invasive.Therefore,laparoscopic radical surgery is safe and feasible for colorectal cancer patients 375 years old,which is worth popularizing in clinical practice. |
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