Meta-Analysis Of Clinical Efficacy Of Traditional Chinese Medicine For Chronic Nephritis And Data Mining Of Director Yang Yulan's Medication For Chronic Nephritis

Research purposes: 1.By comparing the curative effect of traditional Chinese medicine treatment or combined western medicine treatment with western medicine alone for chronic nephritis,analyze the curative effect of traditional Chinese medicine treatment and the improvement of laboratory indicators of chronic nephritis.2.Through data mining and case collection,use IBM SPSS Statistics 23 and IBM SPSS Modeler 18.0 software to establish a database and summarize Professor Yang Yulan's experience in treating chronic nephritis.Research method: 1.Retrieve documents from How Net,Wanfang,and Weipu from the time of database construction to December 2019 with the keyword "chronic nephritis,chronic glomerulonephritis" as the subject term,and use the Revman5.3 software to evaluate the quality of the included documents Perform meta-analysis.2.Collected 203 cases of chronic nephritis in the outpatient department of Director Yang Yulan,recorded the general situation,diagnosis,prescription medication,etc.,and used IBM SPSS Statistics software to perform data mining,and summarized the rule of Director Yang's treatment of chronic nephritis,at the same time,use IBM SPSS Modeler 18.0 software for data mining to find potential new prescriptions.Research result: 1.Meta analysis results: a total of 17 literatures were included,with a total of 1584 cases divided into a control group and an experimental group.Five of these indicators were observed: efficiency,24 h UTP,Scr,BUN,Alb.From the analysis results,It can be seen that traditional Chinese medicine or western medicine in treating chronic nephritis has achieved better clinical results than western medicine alone.2.Data mining revealed that a total of 203 prescriptions were included,with a total of 75 flavors of Chinese medicine.The total cumulative frequency of use was 2938 times,and the frequency of use more than 50 times were: Astragalus,Qingfeng rattan,Hedyotis diffusa,Zelan,Chuanxiong,Earth Poria,Angelica sinensis,Amaranth flower,Lime meat,Ligustrum lucidum,Poria,Poria,Dilong,Curcuma,Cicada,Jin Yingzi,Turmeric 17 flavors,are commonly used by Director Yang to treat chronic nephritis.The top 10 are: Astragalus membranaceus,Qingfeng rattan,Hedyotis diffusa,Zelan,Chuanxiong,Poria cocos,Angelica,Amaranth flower,Liquor meat,Ligustrum lucidum.It is the characteristic medicine of Director Yang for chronic nephritis.Prescription drugs include a total of 15 drug categories,sorted by frequency of use,from blood to blood medicine,tonic medicine,diuretic and dampness medicine,heat-clearing and detoxifying medicine,astringent medicine,hemostatic medicine,antihypertensive medicine,and rheumatism medicine.,Pingganxifeng medicine,heat-drying-dampness medicine,heatclearing and cooling-blood medicine,qi-clearing medicine,heat-clearing and purging-powder medicine,sedative antipsychotic medicine,heat-reducing phlegm medicine.Conclusion: 1.Director Yang Yulan believes that chronic nephritis is the evidence of deficiency and deficiencies,spleen and kidney deficiency and gasification disorder,Sanjiao water channel is unsatisfactory,qi and blood function is abnormal,and water and fluid metabolism is dysregulated,which leads to damp heat,blood stasis,and turbidity.Health.2.The mentor 's treatment of chronic nephritis emphasizes the combination of supporting and eliminating evils,treating both the symptoms and the symptoms,focusing on strengthening Qi and nourishing blood for the deficiency of the spleen,and strengthening the spleen and kidney.Astragalus,Angelica,Ligustrum lucidum,Huang Jing,Jin Yingzi and other beneficial qi and blood are commonly used.Replenishes spleen and kidney,clears away heat and dampness and detoxifies evil blood,promotes blood circulation and removes blood stasis and water.Commonly used Zelan,Tuckahoe and other heat-clearing and promoting blood circulation to increase clinical treatment effect.Pay attention to the efficacy of traditional Chinese medicine while combining modern pharmacological effects,Chinese and Western mutual reference.3.From the analysis of data mining results,combined with Director Yang's clinical experience in treating chronic nephritis,the core group of mentors in treating chronic nephritis is: Hedyotis diffusa + Qingfengteng + shepherd's purse flower,Chuanxiong + Angelica + Astragalus,Astragalus,Jinying Child + Chinese yam + Zelan + Lu Shi.SPSS software suggests that potential new prescriptions include Astragalus,Cornus officinalis,Rhizoma Chuanxiong,Angelica sinensis,and Dilong;Qingfengteng,Hedyotis diffusa,Zephylla,Shepherd's purse flower,Poria cocos;Ligustrum lucidum,Glycyrrhiza glabra,Golden cherry,Curcuma;Salvia,safflower,yellow charcoal,rhubarb charcoal,Centella asiatica,fenugreek,epimedium,scutellaria charcoal;Pakchoi root,agrimony,madder,thistle,lotus house charcoal.4.Through data mining,combined with clinical medication,it is concluded that Yang's commonly used drugs for treating chronic nephritis are astragalus,Qingfengteng,Hedyotis diffusa,Zephylla,Ligusticum chuanxiong,Poria cocos,Angelica,shepherd's purse flower,cornus officinalis,female Sadako.