| The synthesis of graphene-based noble metal nanoparticle composites has been rapidly developed and widely used in the development of electrochemical biosensors.However,the preparation of graphene-based platinum nanoparticles or gold nanoparticles composites still has many problems,such as complicated process,serious pollution and large energy consumption.Gamma irradiation technology of 60Co not only has the characteristics of uniformity,high efficiency and low pollution,but also can crush the size of particles at a higher radiation dose.According to our previous studies,gamma rays can also induce the growth of small interlayer molecules and peel off graphite oxide,and at the same time,the size of metal nanoparticles can be effectively reduced due to the interlayer limiting effect of graphite oxide.Therefore,gamma irradiation is expected to be an ideal preparation method for graphene-based platinum-gold alloy nanoparticle composites.Firstly,this paper studied the growth of platinum alloy nanoparticles induced by gamma ray irradiation of different molar ratios of chloroauric acid and chloroplatinic acid as precursor,so as to obtain graphene-based platinum nanoparticle composites.Subsequently,we found that the nanocomposites of flower-like platinum-gold alloy nanoparticles have a high current feedback signal to hydrogen peroxide.The average size of platinum nanoparticles reaches 15 nm and the limit of electrical detection can reach 0.43 microns.Then,we extend this application to the detection of biological immune sensing.Chloroauric acid and chloroplatinic acid with the same molar ratio were used as precursors.In order to obtain better biosensor performance,different metal end sealants and different irradiation systems were used.It was verified that the synthesized graphene-based platinum nanoparticle composites had a very high sensitivity to the immunosensing detection of carcinoembryonic antigen under the synergistic effect of microemulsion and gamma irradiation. |
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