Professor Wang Sumei's Data Mining Research On The Treatment Of Children's Tic Disorder

Objective:To explore the clinical data of Professor Wang Sumei in treating TD,to analyze the clinical characteristics of TD in Chinese and Western medicine,and to summarize Professor Wang Sumei's syndrome differentiation and medication rules for treating TD.Methods:Choosing a total of 1186 TD scientific research medical records that were established from March 2012 to December 2017 in the Pediatric Tics Clinic of Dongfang Hospital of Beijing University of Chinese Medicine.They were all the first-visit medical records.The wide data study selected 1186 medical records that met all the criteria,and in the deep data study,100 medical records with a relatively recent date of consultation(May 2016 to December 2017)were selected.The data in the scientific research medical record is reviewed and entered into the computer;the data processed and recorded by the information technology is counted,analyzed,and mined;finally,combined with the clinical practice,according to the results obtained by the above data mining,the clinical practice and the theory of traditional Chinese medicine are used to explain the results.Results:(1)The sex ratio of 1186 children with TD was 4.29:1.The youngest age was 2 years old and the oldest was 17 years old.(2)There was no correlation between gender and the diagnostic typing(p=0.990>0.05),TCM syndromes(p=0.068>0.05)and age of treatment(p=0.143>0.05).(3)There was no correlation between TCM syndrome types and living areas(p=0.874>0.05).(4)The most common age distribution was 6-13 years old.(5)There were statistical differences in the diagnostic classification of Western medicine in children with different ages(p<0.01).With the increase of age,the number of transient tic patients decreased and the number of TS patients increased.(6)There were statistical differences in TCM syndrome types among children with TD of different ages(p<0.01).Young children mainly suffer from spleen deficiency and hyperactivity of the liver syndrome.With the increase of age,the prognosis of the syndrome type is mainly in the two directions of liver wind internal disturbance syndrome and phlegm-fire disturbance syndrome.(7)There was no significant difference between the diagnostic classification of modern medicine(p=0.539>0.05)and TCM syndromes(p=0.129>0.05)in children with TD born in different months.(8)There were statistical differences in the diagnostic classification of modern medicine in children with TD with different TCM syndromes(p<0.01).Among them,the children with spleen deficiency and hyperactivity of the liver syndrome have a balanced proportion of the three types of Western medicine diagnosis,and the proportion of TS is less than 50%;the children with liver wind internal disturbance syndrome and phlegm-fire disturbance syndrome are mainly TS,TS accounts for The proportions are all over 50%,while the proportion of transient tic disorder and chronic tic disorder is small.(9)The clinical manifestations of tics were mostly distributed in the head and face.Among them,blinking was the most common twitching performance,and its frequency of occurrence was as high as 71.59%,followed by pharyngeal vocalization and nasal aspiration.(10)The clustering results of two clinical manifestation combinations of TiC were blink-uttering combinations,followed by blink--mouth-twitching and blink—nose-inhalation.The most frequent clinical manifestation combinations were blinking combinations.(11)The clustering results of three combinations of clinical manifestations of TiC were blink-mouth-twitching-uttering and blink-uttering-shrug.(12)Clustering rule analysis of tic and emotional clinical manifestations showed that the clustering rule with the highest confidence was mouth-twitching,uttering->blinking(0.942857143).(13)Professor Wang Sumei's most commonly used medicines for treating TD are uncaria,Fangfeng,Pueraria lobata and tangerine peel.The frequency of warm medicines are the most according to Four Qis.The frequency of pungent and sweet medicines are the most according to Five Flavors.The most common meridians are liver meridian and spleen meridian.Conclusions:(1)Gender,region,and birth month have little to do with the diagnosis of children.(2)Age is related to the diagnostic typing of modern medicine and the classification of TCM syndromes.The younger the patients are,the more likely they are to suffer from transient tic syndrome and spleen deficiency and hyperactivity of the liver syndrome;the older the patients are,the more likely they are to suffer from TS,and the more likely the TCM syndromes are liver wind internal disturbance syndrome and phlegm-fire disturbance syndrome.(3)Spleen deficiency and hyperactivity of the liver syndrome is the most common syndrome of TD.TCM syndromes of TD are related to the diagnosis of modern medicine.TS is the main syndrome in children with liver wind internal disturbance syndrome and phlegm-fire disturbance syndrome.The proportion of three types of modern medicine diagnosis of children with spleen deficiency and hyperactivity of the liver syndrome is relatively balanced,and treatment should be combined with disease and syndrome.(4)Blinking is the most common clinical manifestation of spleen deficiency and hyperactivity of the liver syndrome,and pharyngeal vocalization is the most common clinical manifestation of liver wind internal disturbance syndrome and phlegm-fire disturbance syndrome.(5)Professor Wang Sumei's most commonly used medicines for treating TD are uncaria,Fangfeng,Pueraria lobata and tangerine peel.The frequency of warm medicines are the most according to Four Qis.The frequency of pungent and sweet medicines are the most according to Five Flavors.The most common meridians are liver meridian and spleen meridian.They reflect the academic viewpoint of treating TD from the liver and spleen.