The Effect Of Lianxia Ningxin Granule On The Quality Of Life And Exercise Tolerance Of Patients With Coronary Heart Disease With Phlegm-heat Syndrome

ObjectiveThis research plan is based on summarizing Professor Li Ping's many years of clinical practice experience,and aims to discuss the representative prescription of Qingxin Hua Tan method—Lianxia Ningxin Granule on the traditional Chinese medicine phlegm heat syndrome,quality of life and The impact of exercise tolerance will provide better treatment methods for TCM diagnosis and treatment technology to better serve patients with coronary heart disease and phlegm-heat syndrome in the future.MethodThis study protocol adopted the research method of randomized controlled trials.According to the judgment of professionals,60 enrolled patients who met the enrollment criteria were divided into consecutive groups following the principle of randomized control under the premise of signing informed consent.Lianxia group and control group,30 patients in each group,Lianxia group combined with Lianxia Ningxin granules on the basis of Western medicine basic treatment,and control group was given placebo on the basis of Western medicine diagnosis and treatment routine.The phlegm-heat syndrome scale scores,Seattle scale scores and six-minute walking test results of the patients in the group before and after treatment were statistically analyzed to further verify the TCM symptoms,quality of life and exercise of patients with coronary heart disease and phlegm-heat syndrome after statistical analysis Tolerance effectiveness.Result1.In TCM symptom,no matter in the comparison of the total score of phlegm-heat syndrome scale or the evaluation of curative effect after treatment,the improvement of the total score of phlegm-heat syndrome in patients with coronary heart disease and phlegm-heat syndrome is better than that of the control group.The total score of phlegm-heat syndrome in the group and Lianxia group was significantly improved after 2 weeks of treatment,and the improvement effect after 4 weeks of treatment was significantly better than that after 2 weeks of treatment.In terms of the classification items of the Phlegm-heat Syndrome Scale:after 4 weeks of treatment,Lianxia Ningxin Granules combined with basic Western medicine can significantly improve the chest pain,chest tightness,shortness of breath,chest burning sensation,upset,palpitations in patients with phlegm-heat syndrome of coronary heart disease.Compared with the control group,the clinical symptoms of sputum,yellow sputum,heavy limbs,constipation,epilepsy,dry mouth,and tongue are more improved,and the chest pain,chest tightness,shortness of breath,chest burning sensation,upset,palpitations,Sputum,sputum yellow thick,heavy limbs,constipation and other items in the Lianxia group was significantly better than the control group.2.In terms of quality of life research,statistical analysis of the Seattle scale scores of the two groups can be obtained:30 patients in the Lianxia group after 4 weeks of treatment in the degree of physical restriction,the steady state of angina pectoris,the onset of angina pectoris,treatment satisfaction The five dimensions of the disease and the degree of disease cognition are statistically significant compared with the comparison before treatment,while the Seattle scale score of the control group after treatment is only in the three dimensions of stable angina,treatment satisfaction,and disease cognition.The difference is statistically significant.And the Seattle scale scores of the two groups can be concluded through the comparison between the two groups.The Lianxia group has significant differences in the two dimensions of the stable state of angina and the incidence of angina.3.In terms of exercise tolerance,a comparative analysis of the results of the six-minute walking test between the two groups of patients with coronary heart disease and phlegm-heat syndrome before and after treatment can be concluded:Lianxia Ningxin granule combined with Western medicine basic medicine can improve the exercise tolerance of patients with coronary heart disease and phlegm-heat syndrome,The improvement effect is better than the control group.ConclusionLianxia Ningxin granules not only have a significant improvement effect on TCM syndromes in patients with coronary heart disease and phlegm-heat syndrome,but also can significantly improve the quality of life and exercise tolerance of patients with coronary heart disease and phlegm-heat syndrome.It is worthy of further research and clinical application.